摘要
目的:探讨甲状腺手术中氟比洛芬酯对丙泊酚—瑞芬太尼麻醉效果的影响。方法:将210例择期丙泊酚—瑞芬太尼麻醉下行甲状腺手术患者随机分为对照组和氟比洛芬酯组,每组105例。于切皮前30 min,对照组静脉注入等量生理盐水10mL,氟比洛芬酯组经静脉注入氟比洛芬酯注射液100 mg。分别记录患者麻醉前10 min(T0)、切皮时(T1)、切皮后10 min(T2)、切除腺体时(T3)以及拔管时(T4)的血流动力学(SBP、DBP、HR)的变化以及术后口述描述评分(VRS)。结果:与对照组比较,氟比洛芬酯组T1-4时SP、DP均降低,两组差别有统计学意义(P<0.05)。氟比洛芬酯组离开手术室时无痛率明显高于对照组,两组差别有统计学意义(P<0.05)。结论:氟比洛芬酯对丙泊酚—瑞芬太尼麻醉下行甲状腺手术患者血流动力学影响小,且减轻术后疼痛,术后恢复更为舒适。
Objective： To evaluate the effect of flurbiprofen ester on thyroid surgery patients with propofol-remifentanil anesthesia.Methods： Two hundreds and ten cases of selective thyroid surgery with propofol-remifentanil anesthesia were randomly divided into A and B groups,each group of 105 cases.At 30 minutes before skin incision,we injected normal saline 10 mL in the group A,and injected flurbiprofen ester 100 mg in group B intravenously.We recorded hemodynamics（SBP,DBP,HR） changes 10 min before anesthesia（T0）,during skin incision（T1）,10 min after skin incision（T2）,removal of the gland（T3）,and extubation（T4） and anesthesia recovery and VRS score.Results： Compared with group A,SP and DP in T1-4 group B were lower and the difference between two groups was statistically significant（P〈0.05）.The OAAS score in group B was significantly higher than group A whtn leaving the operating room and the difference between two groups was statistically significant（P〈0.05）.Conclusion： Flurbiprofen ester on propofol-remifentanil anesthesia for thyroid surgery was stable hemodynamic function in patients and better analgesia.
出处
《华西医学》
CAS
2010年第1期71-73,共3页
West China Medical Journal
