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艾滋病暴露前用药的伦理学思考 被引量:3

The Ethical Reflections on Pre Exposure Prophylaxis(PrEP)for Aids Prevention
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摘要 目前有研究提示艾滋病暴露前药物预防能潜在降低感染风险,如果其有效性得到证实将有很大应用前景。然而处于临床阶段的PrEP正面临一系列伦理问题,如性耻感的消解,性行为去抑制,知情与隐私权,受试者生命安全、知情同意、经济承受力。解决好这些伦理问题,是这项新策略顺利进行的重要保障。 Present studies suggest that pre exposure prophylaxis PrEP has the potentiality to reduce HIV infections. PrEP will have great application if it is proved to be effective. However,PrEP in clinical trials is confronted by a number of ethical issues, such as the dissolving of sexual stigma, sexual disinhibition, subjects' privacy and public's right to know, subjects' safety right, informed consent, economical affordability. To solve these ethical issues well is the important guarantee for the smooth progress of this new strategy.
出处 《医学与哲学(A)》 北大核心 2010年第5期20-22,共3页 Medicine & Philosophy:Humanistic & Social Medicine Edition
关键词 艾滋病 暴露前用药 伦理 aids, pre exposure prophylaxis, ethics
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参考文献8

  • 1联合国艾滋病规划署.2009年全球艾滋病流行报告[EB/OL].(2009-11-25)[2009-12-20].http://www.chinaids.org.cn/n16/n1058/297763.html.
  • 2中华人民共和国卫生部.陈竺部长出席第五届中国艾滋病防治国际合作项目经验交流会[EB/OL].(2009-11-24)[2009-12-20].http://www.moh.gov.cn/publicfiles/busjness/htmlfles/mohgjhzs/s3586/200911/44674.htm.
  • 3PrEP Primer: An introduction to pre exposure prophylaxis(PrEP) research for HIV prevention[EB/OL]. (2009-11)[2009-12- 20]. http://www. avae. org/ht/a/GetDocumentAction/i/3302.
  • 4姜晓梅,吕繁.暴露前药物预防:预防HIV感染的潜在新策略[J].疾病控制杂志,2008,12(2):159-163. 被引量:8
  • 5杨柳.性文化视野下的社会分层[J].河南社会科学,2008,16(S1):67-69. 被引量:2
  • 6Baggaley R F, Garnett G P, Ferguson N M. Modeling the impact of antiFetroviral use in resource poor settings [J]. PLoS Med, 2006, 3(4) :e124.
  • 7刘靖,王林.抗逆转录病毒药物的肝毒性[J].国外医学(药学分册),2005,32(5):335-338. 被引量:10
  • 8Paxton L A, Hope T, Jaffe H W. Pre-exposure prophylaxis for HIV infection: what if it works? [J]. The lancet, 2007, 370: 89- 93.

二级参考文献35

  • 1[1]UNAIDS,WHO.2007 AIDS epidemic update[OL].2007 Dec.Available at:http://data.unaids.org/pub/EPISlides/2007/2007_epiupdate_en.pdf.
  • 2[2]STEP study:disappointing,but not a failure[J].Lancet,2007,370(9600):1665.
  • 3[3]FHI.FHI Closes Phase III Trial of Cellulose Sulfate for HIV Prevention[OL].Jan.31,2007.http://www.fhi.org/en/AboutFHI/Media/Releases/res_CS_Nigeria.htm
  • 4[4]LiZ Highleyman.New Approaches to HIV Prevention[OL].Winter 2007.http://www.the body.com/content/art 40750.html.
  • 5[5]CDC.CDC Trials of Pre-Exposure Prophylaxis for HIV Prevention[OL].http://prepwatch.org/pdf/Trials/CDC_trials_April.2007.pdf
  • 6[6]Hosseinipour M,Cohen MS,Vernazza PL,et al.Can antiretroviral therapy be used to prevent sexual transmission of human immunodeficiency virus type 1[J].Clin Infect Dis,2002,34(10):1391-1395.
  • 7[7]Connor EM,Sperling RS,Gelber R,et al.Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment.Pediatric AIDS clinical trials group protocol 076 study group[J].N Engl J Med,1994,331(18):1173-1180.
  • 8[8]Guay LA,Musoke P,Fleming T,et al.Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala,Uganda:HIVNET 012 randomised trial[J].Lancet,1999,354(9181):795-802.
  • 9[9]Vyankadondera J,Luchters S,Hassink E,et al.Reducing risk of HIV-1 transmission through breastfeeding using antiretroviral prophylaxis in infants (SIMBA study)[OL].2nd IAS Conference on HIV Pathogenesis and Treatment.July 13-16,2003.Abstract LB7.http://www.iasociety.org/Default.aspx?pageId=11&abstractId=11061
  • 10[10]Cardo DM,Culver DH,Ciesielski CA,et al.A case-control study of HIV seroconversion in health care workers after percutaneous exposure.Center for disease control and prevention needlestick surveillance group[J].N Engl J Med,1997,337(21):1485-1490.

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