摘要
人乳头瘤病毒(HPV)L1蛋白是HPV的主要衣壳蛋白。L1蛋白的表达缺失,将弱化宫颈局部的免疫效应,异常增殖细胞得以生存并将致疾病进展。HPVL1蛋白的功能及其在甄别有潜在恶性可能的宫颈病变患者中具有重要价值。
Human papillomavirus （HPV） L1 protein is the major HPV capsid protein. Lack of HPV L1 protein may occur to reduce immune responses in cervix, thereby promoting the disease progression caused by the abnormal proliferation of cells. This paper discusses the function of HPV LI protein and investigates the clinical application of HPV LI protein in identifying patients at risk of progressive cervical lesions from those infected with HPV.
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
2010年第5期352-355,共4页
Chinese Journal of Practical Gynecology and Obstetrics
关键词
宫颈病变
人乳头瘤病毒
L1蛋白
cervical intraepithelial neoplasia
human papillomavirus
LI capsid protein
