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人乳头瘤病毒分型检测在临床工作中的应用 被引量:29

Clinical detection and genotyping of HPV
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摘要 持续性高危型人乳头瘤病毒(HPV)感染导致宫颈病变和宫颈癌发生学说的确立,促使高危型HPV检测广泛应用于临床工作中。该文阐述了高危型HPV分型检测在宫颈癌及癌前病变中筛查、非典型鳞状上皮不能明确意义(ASC-US)病人的分层管理、阴道镜检查的适应证、宫颈上皮内瘤变(CIN)治疗后残留或复发病变的预测及随访以及指导HPV疫苗的研究与使用。 It has been established that persistent high-risk human papillomavirus (HPV) infection is the main cause of cervical cancer and its cervical lesions. Currently, the high-risk HPV detection is widely used in clinical testing. We summarized the clinical value of HPV genotyping in cervical-cancer and cervical precancerous lesions screening, the triage for atypical squamous cells of undetermined significance(ASC-US) , the indications for the colposcopy test, prediction of the residual or recurrent of high-grade cervical intraepithelial neoplasia (CIN2 and CIN3 ) after treatment and the research and the use of HPV vaccine.
作者 廖秦平 赵健
出处 《中国实用妇科与产科杂志》 CAS CSCD 北大核心 2010年第5期331-333,共3页 Chinese Journal of Practical Gynecology and Obstetrics
关键词 人乳头瘤病毒 宫颈上皮内瘤变 human papillomavirus cervical intraepithelial neoplasia
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参考文献15

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二级参考文献28

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