摘要
目的探讨经皮冠状动脉介入(PCI)治疗对冠心病合并左心功能不全患者心功能的影响。方法选择62例行PCI的冠心病合并左心功能不全患者(PCI组),并选择同期基线资料相似的60例单纯应用药物治疗的冠心病合并左心功能不全患者作对照组。分别于PCI术前(或药物治疗前)及术后(或药物治疗后)6个月进行心脏彩色多普勒检测,比较2组心脏左室舒张末内径(LVDd)、左室收缩末内径(LVDs)、左室射血分数(LVEF)及左室短轴缩短率(FS)的变化,并依据临床表现比较2组NUHA心功能分级的改变。结果2组患者治疗6个月后,彩色多普勒检测各项左心功能指标均较治疗前明显改善(P均<0.05),且PCI组治疗后与对照组比较,其LVDd〔(45.26±12.85)vs(47.71±13.09)mm〕、LVDs〔(29.75±0.91)vs(31.06±0.61)mm〕、LVEF〔(50.56±5.91)%vs(47.62±8.52)%〕和FS〔(28.15±2.98)%vs(23.98±3.05)%〕四项指标均优于对照组(P均<0.05)。PCI组患者心功能(NYHA)改善情况优于对照组。结论PCI治疗可明显改善冠心病合并左心功能不全患者的心功能。
Objective To explore the impact of percutaneous coronary intervention （PCI） on left heart failure in patients with coronary heart disease.Methods Sixty-two patients with coronary heart disease combined with left heart failure underwent PCI （PCI group）were studied,and 60 patients with the similar condition treated by drugs were served as control（control group）.Both the two groups were detected by echocardiography before and six months after received treatment.Left ventricular end-diastolic diameter （LVDd）,left ventricular end-systolic diameter （LVDs）,left ventricular ejection fraction （LVEF）,left ventricular fractional shortening （FS） and NYHA grading according to clinical manifestation were compared.Results LVDd,LVDs,LVEF,FS and NYHA grading were all improved 6 months after treatment in two groups.Aforementioned indexes of heart function in PCI group were significantly improved than those in control group（all P〈0.01）.Conclusions The left ventricular function in patients with coronary heart disease is significantly improved after PCI.
出处
《中国临床研究》
CAS
2010年第5期368-369,共2页
Chinese Journal of Clinical Research
关键词
经皮冠状动脉介入术
冠心病
心功能不全
Percutaneous coronary intervention
Coronary heart disease
Heart failure
