摘要
目的探讨双歧三联活菌治疗亚临床肝性脑病(SHE)的疗效。方法经智力测验(数字连接试验)诊断SHE64例,随机分为对照组和治疗组各32例。对照组服复合维生素B,治疗组服双歧三联活菌片,25周为1疗程。治疗前后测定血氨、丙氨酸转氨酶、数字连接试验,统计治疗期间肝性脑病(HE)的发病率。结果治疗组治疗后血氨、ALT、NCT较治疗前显著改善,且明显优于对照组(P<0.05或P<0.01),治疗组HE发病率显著低于对照组(P<0.01)。结论双歧三联活菌维持治疗SHE能够降低血氨,改善智力测验结果,降低HE的发病率。
Objective To observe the clinical effects of bifid triple viable on the treatment of subclinical hepatic encephalopathy(SHE). Methods 64 SHE patients conformed by psychometric performance(number connection test) were randomly divided into study group( 32 cases ) and control group (32 eases). The eonerol group was treated with compound vitamin B, the study group was treated with bifid triple viable. All treated for 24 weeks. Blood ammonia, ALT, number connection test were investigated;the incidence of hepatic encepbalopathy(HE) was recorded. Results After treatment,blood ammonic,ALT,and number connection test in study group were improved greatly, and three were significant differences between the two group( P 〈 0.05 or P 〈 0. 01 ) ;the HE incidence of study group was lower than that of control group ( P 〈 0.05 ). Conclusion Bifid triple viable treatment can decrease blood ammonia, improve the psychometric performance and decrease the incidence of HE.
出处
《临床消化病杂志》
2010年第2期105-106,共2页
Chinese Journal of Clinical Gastroenterology
关键词
亚临床肝性脑病
智力测验
双歧三联活菌
Subclinical hepatic encephalopathy
Psychometric performance
Bifid triple viable