摘要
目的探讨3.0T磁共振对比剂动态增强扫描量化参数在肝脏实性占位性病变鉴别诊断中的价值。方法利用3.0T磁共振对113个肝脏占位性病变进行对比剂动态增强扫描,分别测量各个病灶的动态增强曲线类型、最大上升斜率(MSI)、信号增强率(SER)、正性增强积分(PEI)、最大下降斜率(MSD)和峰值(PV),分析以上各参数在不同病变之间的差异。结果肝细胞癌(HCC)与除局灶性结节增生(FNH)外的各病,肝转移瘤与海绵状血管瘤、FNH及肝脓肿,FNH与海绵状血管瘤及肝脓肿之间强化曲线类型具有统计学差异(P<0.05)。海绵状血管瘤与其余各病,HCC与除FNH外的各病,FNH与肝转移瘤、肝内胆管细胞癌及肝脓肿,肝转移瘤与肝脓肿之间的MSI、PEI、MSD及PV存在统计学差异(P<0.05)。6种病变之间的SER未见统计学差异(P>0.05)。结论肝脏实性占位性病变的动态增强曲线类型和量化参数存在不同程度的差异,将两者结合有助于其鉴别诊断。
Objective To explore the role of some quantitative parameters of dynamic contrast-enhanced magnetic resonance imaging （DCE-MRI） at 3. 0 Tesla in differential diagnosis of hepatic masses. Methods DCE-MRI was performed on 113 patients with hepatic masses. The curve types of DCE-MRI and some quantitative parameters including the maximum slop of increase （MSI）,signal enhancement ratio （SER）,positive enhancement integral （PEI）,maximum slop of decrease （MSD）,and peak value （PV） of hepatic masses were measured. The differences of the curve types and quantitative parameters in different hepatic masses were compared and analyzed. Results There were significant differences in enhanced curve type between hepatocellular carcinoma （HCC） and other masses except for focal nodular hyperplasia （FNH）,between metastases and hemangioma FNH,as well as hepatic abscess,and between FNH and hemangioma as well as hepatic abscess （P〈 0. 05）. Also,there were significant differences in MSI,PEI,MSD, and PV between hemangioma and other masses,between HCC and other masses except for FNH,between FNH and metastases,intrahepatic cholangiocarcinoma,as well as hepatic abscess,and between metastases and hepatic abscess （P〈 0. 05）. However,no difference in SER of the six kinds of hepatic masses was found （P〉0. 05）. Conclusion There are some differences in enhanced curve types and quantitative parameters of DCE-MRI of hepatic masses,and the combination of these two methods may be helpful for the differential diagnosis of hepatic masses.
出处
《山东大学学报（医学版）》
CAS
北大核心
2010年第4期139-141,146,共4页
Journal of Shandong University:Health Sciences
关键词
肝脏占位性病变
动态增强磁共振成像
鉴别诊断
Hepatic mass
Dynamic contrast-enhanced magnetic resonance imaging
Differential diagnosis
