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醋酸奥曲肽治疗重症急性胰腺炎的临床观察 被引量:8

Clinical effects of octreotide acetate on severe acute pancreatitis
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摘要 目的:探讨善宁治疗重症胰腺炎的临床疗效。方法:将60例重症胰腺炎患者随机分成治疗组和对照组各30例,对照组予常规治疗,治疗组在常规治疗基础上加用醋酸奥曲肽(善宁)。观察了两组治疗的前后血清淀粉酶含量变化,并对比分析两组之间有效率。结果:治疗组的血清淀粉酶下降明显低于对照组(P<0.05),有效率高于对照组(P<0.05)。结论:善宁能有效降低重症胰腺炎患者的血清淀粉酶含量有明显疗效。 Objective: To observe the clinical effects of octreotide in the treatment of patients with severe acute pancreatitis. Methods : 60 cases of acute pancreatitis were divided into octreotide treatment group ( n = 30 ) and control group ( n = 30 ) at random. Subjects in the treatment group were treated with octreotide in addition to the routine treatment while those in the control group were only given the routine treatment. Serum amylase level was quantitatively analyzed before and after the treatment course. Effective rate was compared between the two groups. Results: The serum amylase concentration of the subjects of the treatment group was significantly lower than that of the control group (P 〈 0.05 ) and the effective rate also significantly higher than that of the control group (P 〈 0.05). Conclusions: Octreotide can decrease greatly the levels of serum amylase, exhibiting obvious therapeutic effects on severe acute pancreatitis.
作者 郭洪寅
出处 《天津药学》 2010年第2期39-40,共2页 Tianjin Pharmacy
关键词 善宁 重症胰腺炎 血清淀粉酶 Octreotide, severe acute pancreatitis, amylase
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