摘要
目的:观察肝素钠治疗羊水过少的疗效。方法:126例羊水过少的患者随机分为研究组和对照组各63例,均静脉补液1 000 ml,研究组同时加入肝素钠6 250 U静脉滴注,疗程7 d,治疗后复查羊水指数,分娩时观测新生儿Apgar评分、新生儿体重、分娩方式及产后出血。结果:治疗后研究组羊水指数较对照组明显升高,差异有显著性;研究组新生儿窒息率低,出生体重高,剖宫产率低;两组产后出血量比较差异无显著性。结论:肝素钠治疗羊水过少,显著增加羊水指数,减少新生儿窒息率并增加新生儿体重,降低剖宫产率,对产后出血无影响。
Objective： To observe the curative effect of heparin sodium on oligohydramnios. Methods： 126 pregnant women with oligohydramnios were randomly allocated into two groups on average, investigational group and control group. 1000 ml of 5% glucose solution was intravenously infused to both group for seven days, and 6 250 U of heparin sodium was added to the investigational group. Amniotic fluid index（AFI） was rechecked after the seven - day infusion. Apgar score and body weight of a newnate, delivery way, and post partum hemoorhage were observed while delivering. Results ： AFI and the neonatal body weight for the investigational group was significantly higher than that for the control group. The neonatal asphyxia rate and the caesarean rate for the investigational group were significantly lower than those for the control group. There was no significant difference in postpartum hemorrhage between the two groups. Conclusions： Heparin sodium could be used for the treatment of oligohydramnios. It can increase AFI and can put on neonatal weight obviously, and can decline the rate of the neonatal asphyxia and the rate of caesarean birth, but it can not increase the postpartum hemorrhage.
出处
《天津药学》
2010年第2期26-27,共2页
Tianjin Pharmacy
