摘要
研究自体血清局部注射对腰背肌损伤的治疗效果。建立动物模型,分组对照研究。共将实验动物分为四组,通过手术造成小鼠腰背部肌肉损伤。之后,在损伤的局部注射生理盐水,或原浓度的自体血清、二倍浓缩的自体血清、四倍浓缩的自体血清。在术后第2、4、7日分别测得各组小鼠腰背肌肌力,求四组小鼠腰背肌肌力的平均值及标准差,比较组内及组间的差异。最后,对实验结果进行了综合分析和讨论。自体血清局部注射处理的小鼠,肌力恢复更加明显,愈合后肌力明显增强,术后第7日各组肌力平均值具有显著性差异,以生理盐水注射组为对照组,原浓度血清组、二倍浓缩组、四倍浓缩组平均腰背肌力均高于对照组。动物模型验证了自体血清局部注射疗法在腰背肌损伤的动物模型中是有效的,可以促进腰背肌损伤的修复和愈合。
To evaluate the effects of using autologous serum in the treatment of lumbar muscle injury,in the group control experiment, we have established the animal models of lumbar muscle injury in 9-11-week-old C57 mice. There were total of four groups of animal models. In Each group, we randomly selected 10 mice. We made animal models through operations. Then, operator injected normal saline or original serum into the injury site. We measured lumbar muscle strength of mice after the first 2/4/7 days, calculated the average and standard deviation, and compared differences. Finally, the results were analyzed and discussed.In Group 2, 3, 4, muscle strength restored more evident, the average strength of the groups had significant difference. The means of Group 2/3/4 are higher than Group 1,the control group.In animal models, it was a good outcome of autologous serum in the treatment of lumbar muscle injury. The restoration and healing of lumbar muscle injury can be promoted.
出处
《医学与哲学（B）》
2010年第4期51-53,共3页
Medicine & Philosophy(B)
关键词
自体血清
细胞因子
腰背肌
运动损伤
autologous serum, cytokine, lumbar muscle, sports injury
