期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

机械通气辅助治疗12例手足口病并发神经源性肺水肿患儿的临床观察 被引量：8

原文传递
导出
摘要 目的探讨机械通气辅助治疗手足口病并发神经源性肺水肿(NPE)患儿的临床效果。方法对12例手足口病并发NPE的患儿在给予丙种球蛋白、甲基强的松龙和降颅压、改善循环等对症治疗的同时应用机械通气治疗,主要采用同步间歇指令性通气(SIMV)和呼气末正压通气(PEEP)。结果行SIMV联合PEEP治疗后绝大部分患儿临床症状逐渐改善,病情稳定后逐步调整呼吸机参数并成功撤机。结论对手足口病并发NPE的患儿及时采取机械通气治疗可显著提高抢救成功率,降低病死率。
作者 宋斌
机构地区 山东省泰安市妇幼保健院儿内三科
出处 《临床医学》 CAS 2010年第4期92-93,共2页 Clinical Medicine
关键词 手足口病 神经源性肺水肿 机械通气
分类号 R725.1 [医药卫生—儿科]
  • 相关文献

参考文献3

二级参考文献38

  • 1陈宗波.人类肠道病毒71型感染的研究进展[J].中华儿科杂志,2005,43(6):428-430. 被引量：102
  • 2王娟,周颖玲.神经源性心脏损害的研究现状[J].实用医学杂志,2006,22(23):2817-2819. 被引量：12
  • 3Chang LY, Lin TY, Huang YC, et al. Comparison of enterovirus 71 andcoxsackievirus A16 clinical illnesses during the Taiwan enterovirusepidemic, 1998. Pediatr Infect Dis J, 1999, 18 (12): 1092-1096.
  • 4Huang CC, Liu CC, Chang YC, et al. Nrurologic complications in children with enterovirus 71 infection. N Engl J Med, 1999, 341 (13) :936-941.
  • 5Ho M, Chen ER, Chen ER, et al. Enterovirus Epidemic Working Group. The enterovirus type 71 epidemic of Taiwan, 1998. N Engl J Med, 1999,341(13) :929-935.
  • 6Lin TY, Chang LY, Hsia SH, et al. The 1998 Enterovirus 71 outbreak in Taiwan: pathogenesis and management. Clin Infect Dis, 2002, 34 (3) : S52-57.
  • 7Wu JM, Wang JN, Tsai YC, et al. Cardiopulmonary manifestations of fulminate enterovirus 71 infection. Pediatrics, 2002, 109 (2) :e26.
  • 8Hsueh C, Jung SM, Shih SR, et al. Acute encephalomyelitis during an outbreak of enterovirus type 71 infection in Taiwan:report of an autopsy case with pathologic, immunofluorescence, and molecular studies. Mod Pathoh 2000, 13( 11 ) : 1200-1205.
  • 9Ho M. Enterovirus 71 : the virus, its infections and outbreaks. J Microbiol Immunol Infect, 2000, 33:205-216.
  • 10MeMinn PC. An overview of the evolution of enterovirus 71 and its clinical and public health significance. FEMS Microbiology Reviews, 2002, 26:91-107.

共引文献273

同被引文献60

  • 1钟天鹰,陈倩,胡正.荧光定量PCR检测手足口病患儿肠道病毒RNA[J].中国当代儿科杂志,2010,12(2):145-146. 被引量：8
  • 2胡亚美 江载芳.诸福棠实用儿科学[M]第7版[M].北京:人民卫生出版社,2002.1514.
  • 3Wu Y, Yeo A, Phoon MC, et al. The largest outbreak of hand ; foot and mouth disease in Singapore in 2008 : The role of entero- virus 71 and coxsackievirus A strains [ J ]. IntJ Infect Dis, 2010, 14(2) :e1076-e1081.
  • 4Chang LY, Huang LM, Gan SS, et al. Neurodevelopment and cognition in children after enterovirus 71 infection[ J]. N Engl J Med, 2007, 356(12):1226-1234.
  • 5Wang SM, Liu CC. Enterovirus 71 : epidemiology, pathogenesis and management [ J ]. Expert Rev Anti Infect Ther, 2009, 7 (6) :735-742.
  • 6Qiu j. Enterovirus 71 infection: a new threat to global public health[J]. Lancet Neurol, 2008, 7(10):868-869.
  • 7Ma E, Fung C, Yip SH, et al. Estimation of the basic reproduc- tion number of enterovirus 71 and coxsackievirus A16 in hand, foot, and mouth disease outbreaks [ J ]. Pediatr Infect Dis J, 2011,30(8) :675-679.
  • 8Ooi M, Wong SC, Mohan A, et al. Identication and validation of clinical predictors for the risk of neurological involvement in chil- dren with hand, foot, and mouth disease in Sarawak[J]. BMC Infect Dis, 2009,9:3.
  • 9Yeo WM, Chow VT. The VP1 structural protein of enterovirus 71 interacts with human omithine decarboxylase and gene trap ankyrin repeat[J]. Microb Pathog, 2007, 42 (4) : 129-137.
  • 10Chen CS, Yao YC, Lin SC, et al. Retrograde axonal transport: A major transmission route of enterovirus 71 in mice[ J]. J Clin Virol, 2007, 81(17):8996-9003.

引证文献8

二级引证文献17

临床医学
2010年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部