摘要
目的：探讨附睾粘膜相关淋巴组织（ＭＡＬＴ）型淋巴瘤与附睾肉芽肿性炎的诊断、鉴别诊断及其发病机制。方法：手术切除标本常规石蜡切片和免疫组化ＡＢＣ法标记。结果：４例附睾ＭＡＬＴ型淋巴瘤均为ＣＣＬ细胞型，并有淋巴上皮病变。免疫表型４例ＬＣＡ、Ｌ２６均呈阳性，ＩｇＭ·κ２例，ＩｇＧ·κ１例及ＩｇＡ·λ１例呈阳性。结论：附睾ＭＡＬＴ型淋巴瘤大多为低度恶性，以手术治疗为主，应对附睾慢性炎进行病因治疗，以免附睾形成获得性ＭＡＬＴ。
Purpose To study the diagnosis, differentiation and mechanism of epididymis mucosaassociated lymphoid tissue type lymphoma (EMALTT) and epididymitis. Methods Morpholigic feafures were observed in HE staining section and immunohistochemical ABC method was used. Results The morphology of all four cases indicates the type of centrocyticlike (CCL) cell with formation of lymphoepithelial lesion. Immunophenotypic results were General paraffinsection and immunohistochemical method were marked in surgical specimens. CA+,L26+(4 cases), IgM·κ+(2 cases),IgG·κ+(1 case),IgA·λ+(1 case). Conclusion Most of EMALTT are low grade malignant tumors. Therefore, operation is the first choice. Therapy of epididymitis shoud be taken so that it does not result in acquiring MALT and develope into MALTToma.
出处
《临床与实验病理学杂志》
CAS
CSCD
1998年第3期241-243,I033,共4页
Chinese Journal of Clinical and Experimental Pathology
基金
江苏省自然科学基金
关键词
病理学
附睾肿瘤
淋巴病
MALT型
epididymis
testicular neoplasms
lymphoma
granuloma
pathology, clinical
immunohistochemistry
