摘要
目的 :探讨双侧附睾原发性恶性淋巴瘤的临床病理特征。方法 :报道 1例 4 2岁双侧附睾原发性恶性淋巴瘤 ,手术标本经光镜及免疫组化检查 ,并进行文献复习。结果 :表现为无痛性双侧附睾肿大 ,病理诊断为黏膜相关淋巴组织结外边缘区B细胞恶性淋巴瘤。免疫表型CD4 5、CD2 0、CD79α阳性 ,CD4 5RO、CD3、细胞角蛋白 (CK)、胎盘碱性磷酸酶 (PLAP)阴性。结论 :双侧附睾原发性恶性淋巴瘤极为罕见 ,根据组织学特点 ,结合免疫组化染色 ,可以明确诊断。
Objective::To study the clinical and pathological features of primary malignant lymphoma of the bilateral epididymus.Methods:The surgical specimens of a 42-year-old man with primary malignant lymphoma of the bilateral epidiymus were observed by light microscopy and immunohistochemistry,and the literature was reviewed.Results:The patient presented with painless bilateral epididymal enlargement and the extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue(MALT) was diagnosed by histopathology.The expression of CD45,CD20 and CD79α in the tumor cells was positive,while the expression of CD45RO,CD3,cytokeration(CK) and placental alkaline phosphatase(PLAP) was negative.Conclusions:Primary malignant lymphoma arising in the epididymis is a rare entity.The diagnosis mainly relies on histopathological and immunohistochemical findings.
出处
《蚌埠医学院学报》
CAS
2004年第4期341-342,共2页
Journal of Bengbu Medical College
关键词
附睾肿瘤
恶性淋巴瘤
病理学
临床
epididymal neoplasms
malignant lymphoma
pathology,clinical
