摘要
目的:建立了中药材中13种N-甲基氨基甲酸酯农药残留量的高效液相分析方法。方法:样品用丙酮提取,经凝胶渗透色谱净化,通过柱后衍生,荧光检测器测定农药残留量。结果:除涕灭威和涕灭威亚砜外,3个水平回收率均在75.7%～102.3%,相对标准偏差为0.4%～7.0%。方法检测限为0.01 mg·kg^(-1),定量限为0.03 mg·kg^(-1)。在7种中药材中均未检出农药残留。结论:本方法灵敏,准确,适用于中药材中13种N-甲基氨基甲酸酯农药残留的检测。
Objective：To establish a method for determination of 13 N - methylcarbamates in traditional Chinese medicines.Method：The samples were extracted with acetone and cleaning up with GPC.The pesticides were separaed by HPLC with postcolumn derivatization and detected with fluorescence detector.Result：Except for aldicarb sulfoxide and aldicarb,the average recoveries in three levels were 75.7%- 102.3%with relative standard deviations （RSD） between 0.4%-7.0%.The limits of detection（LOD） were 0.01 mg·kg^-1,and the limits of quantitation （LOQ） were 0.03 mg·kg^-1.The pesticide residues were not detected in all 7 kinds of TCMs.Conclusion： The method is sensitive,accurate and suitable for determination of 13 N - methylcarbamates residues in TCMs.
出处
《药物分析杂志》
CAS
CSCD
北大核心
2010年第4期668-672,共5页
Chinese Journal of Pharmaceutical Analysis
