摘要
目的观察静脉应用双膦酸盐治疗原发骨质疏松痛的疗效。方法原发骨质疏松症患者68例,根据骨密度(BMD)降低的情况(通常用T表示),将患者分为3组,依据T值及年龄,予以静脉因卡膦酸二钠,治疗期间所有组均同时口服钙尔奇D,使用数字模拟评分法(VAS)及双能X线骨密度测定仪(DEXA),测定治疗前后的骨密度评定疗效,并进行统计学分析。结果治疗后患者疼痛强度明显降低(P<0.05),骨密度较前略有增高(P>0.05),副作用轻微可耐受。结论静脉应用双膦酸盐治疗骨质疏松疼痛,有给药方便、依从性好、安全性高、起效快、疗效优等特点,可供临床选用。
Objective To assess the management of primary osteoporosis pain using diphosphonate intravenously.Methods 68 patients with primary osteoporosis pain were divided into three groups by the loss conditions of bone mineral density（commonly use T to express）,according to T score and age,the incadronate disodium was injected.All the groups were given calcium orally during the treatment.The visual analogy scales（VAS）were measured,and the bone mineral density were examined by DEXA before and after treatment.Results The pain intensity significantly decreased after the treatment without apparent adverse effects（P0.05）,T score of bone mineral density slightly increased after treatment（P0.05）.Conclusion The results suggest that it is convenient,adherence,safe,quick and effective on the management of primary osteoporosis pain by diphosphonate intravenous.
出处
《实用药物与临床》
CAS
2010年第2期109-110,共2页
Practical Pharmacy and Clinical Remedies
关键词
双膦酸盐
静脉应用
原发骨质疏松
疼痛
骨密度
Diphosphonate
Intravenous
Primary osteoporosis
Pain
Bone mineral density
