摘要
[目的]了解淀山湖区微囊藻毒素-LR(MC-LR)的污染状况及当地居民肝功能指标的水平。[方法]于2008年5～9月,对淀山湖区的东部、南部、西部、北部及中部5个监测点的水样进行连续监测,监测指标包括总磷(TP)、总氮(TN)、浊度、pH值、耗氧量(COD)和MC-LR;同时,选取在淀山湖区生活10年以上且常年接触淀山湖水的青浦区金泽社区陈东村120名居民为观察组,以不接触淀山湖水,且无肝脏损伤的青东地区某企业员工122人为对照组,检测血清谷丙转氨酶(ALT)、谷草转氨酶(AST)、谷氨酰转肽酶(GGT)、乳酸脱氢酶(LDH)四项指标水平。[结果]淀山湖水的pH值为7.94,呈弱碱性,浊度20.92度,耗氧量为5.28mg/L。淀山湖水中TP浓度、TN浓度分别在0.06～0.31μg/mL和0.2～6.3μg/mL之间波动,均超过了《中华人民共和国地表水环境质量标准》(GB3838—2002)中III类标准,TN/TP的范围在0～54.4之间,水中MC-LR浓度为0.0085μg/L。观察组居民血清AST、LDH和GGT活性均高于对照组,差异有统计学意义(P<0.05)。两组间血清ALT活性差异无统计学意义(P=0.574)。观察组中2人血清指标高于正常值,对照组均在正常范围内。[结论]淀山湖区水体呈一定的富营养化,且存在MC-LR污染,长期生活在该地区的居民健康可能受到一定程度的影响。
[ Objective ] To study the pollution level of microcystin and its effect on the liver function of residents living around Dianshan lake. [ Methods ] Selecting 5 sites in east, west, north, south and middle in the lake as the monitoring points, samples were collected during May to September in 2008, then total phosphorus（ TP ）, total nitrogen（ TN ）, pH, turbidity, COD and microcystin-LR （ MC-LR ）were continually analyzed. At the same period, a serum epidemiological study was carried out in 120 local residents around the lake who lived there for more than 10 years. Another 122 factory workers were chosen as control whose working and living environment were not affected by Dianshan lake. [ Results ] In the water samples, pH was 7.94, turbidity was 20.92, COD was 5.28mg/L, TP was in the level of 0.06 to 0.31μg/ml, TN was 0.2 to 6.3μg/ml, and TN/TP ratio was ranged between 0-54.4. The water samples also showed the Dianshan lake was polluted by MC-LR as its concentration reached 0.0085 μg/L. It was more serious in summer and autumn. Compared with control group, the activity of AST, LDH and GGT in the serum of local residents were all higher with significant difference（ P 〈 0.05 ）, but ALT showed no difference between the two groups（ P = 0.574 ）. [ Conclusion ] Dianshan lake have been polluted by MC-LR, The liver function of residents living around Dianshan lake for a long time may be affected by the pollution.
出处
《环境与职业医学》
CAS
北大核心
2010年第3期153-155,共3页
Journal of Environmental and Occupational Medicine
基金
上海市卫生局青年课题项目资助(编号:2007y12)
上海市疾病预防控制中心小百人培养计划资助(编号:区-207-2)
关键词
淀山湖
微囊藻毒素-LR
卫生调查
水污染
健康影响
Dianshan lake
microcystin-LR（MC-kR）
health survey
water pollution
effects on health
