摘要
淡水水体的富营养化导致了蓝藻水华的普遍发生,微囊藻毒素是由蓝藻的部分藻属产生的环肽化合物,具有毒性大、分布广、结构稳定等特性,从而成为水环境中的重要潜在危害物质。微囊藻毒素已被证明具有明显的肝毒性,是肝肿瘤的促进剂之一。本文就微囊藻毒素的污染现状、肝毒性作用及其促肝癌机制等方面的研究进展进行了综述。
Eutrophication of fresh water lakes and ponds has caused the occurrence of cyanobacteria. Microcystins （MCs）is a class of toxic cyclic heptapeptide, which may be produced by some strains of various blue-green algae. It has become potential hazardous material in aquatic environments for its toxic, distribution and stability. MCs has been showed to be extremely potent hepatotoxins and been viewed as a promoter of liver tumor. In this review, the pollution condition of MCs and its hepatotoxins as well as its mechanisms have been summarized.
出处
《卫生研究》
CAS
CSCD
北大核心
2006年第3期377-379,共3页
Journal of Hygiene Research
关键词
微囊藻毒素
肝毒性
肝癌
促癌作用
microcystins, hepatotoxin, liver tumor, tumor promotion
