罗哌卡因复合芬太尼椎管内分娩镇痛对产程及宫缩的影响

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摘要分娩痛是产妇分娩时经历的一种剧烈疼痛，现国内外要求分娩镇痛的产妇越来越多。而关于分娩镇痛是否对宫缩有影响一直存在争议。本文采用低浓度罗哌卡因复合小剂量芬太尼椎管内分娩镇痛，通过临床观察及检测前列腺素（PGE2）、一氧化氮（NO）水平来评估分娩镇痛对子宫收缩的影响。

作者叶兴宏连庆泉金胜威卢园园胡明品李军陈素华

机构地区温州医学院附属第二医院麻醉科温州医学院附属第二医院产科

出处《浙江医学》 CAS 2010年第3期376-377,共2页 Zhejiang Medical Journal

关键词低浓度罗哌卡因分娩镇痛复合芬太尼椎管内宫缩产程小剂量芬太尼产妇分娩

参考文献7

1Collis R E,Davies D,Areling W,et al.Compaison of combined spinal epidural and standard epidural analgesia in labour[J].Cancel,1995,345:13-16.
2冯丹,姚尚龙,张小铭.硬膜外分娩镇痛对产妇子宫收缩的影响[J].中华麻醉学杂志,2004,24(12):893-895. 被引量：39
3Izum i H,Yallampalli C,Garfield R E.Gestational changes inlarginine-induced relaxation of P regnant rat and humanmyometrial smoo th mucle[J].Am J Obstet Gyneco Ⅰ,1993,169:1327.
4Wetzka-B,Schafer W R,Stehmans A,et al.Effects of nitric oxide donors on the contractility and prostaglandin synthesis of myometrial strips from pregnant and nonpregnant women[J].Gyneco 12Endocrino 1,2002,15(1):34-42.
5Yo shida,Sagawa,ltoh,et al.N itric oxide Increases matrixmetallop roteinase1 production in human uterine cervical fibroblast cells[J].Mo 12Hum-Reprod,2001,7(10):979-985.
6Keelan J A,Coleman M,Mitchell M D,et al.The molecular mechanisma of term and prerem labor:recent progress and clinical implications[J].Clin Obstet Gynecol,1997,40:460-478.
7Alfaidy N.Xiong Z G,Myatt L,et al.Prostaglanfin E2 alpha potentiates cortisol production by stimulating 11beta-hydroxysteroid dehydrOenase 1:a novel feedback loop that may contribute to human labor[J].J Clin Endocrinol Metab,2001,86:558-559.

1Keelan JA, Coleman M, Mitchell MD. The molecular mechanisms of term and preterm labor: recent progress and clinical implications. Clin Obstet Gynecol, 1997, 40:460-478.
2Challis JRG, Matthews SG, Gibb W, et al. Endocrine and paracrine regulation of birth at term and preterm. Endocr Rev, 2000, 21: 514-550.
3Alfaidy N, Xiong ZG, Myatt L. Prostaglandin E2 alpha potentiates cortisol production by stimulating llbeta-hydroxysteroid dehydrogenase 1: a novel feedback loop that may contribute to human labor. J Clin Endocrinol Metab, 2001, 86: 5585-5592.
4McLean M, Smith R. Corticotrophin-releasing hormone and human parturition. Reproduction, 2001, 121: 493-501.
5Challis JR, Sloboda DM, Alfaidy N, et al. Prostaglandins and mechanisms of preterm birth. Reproduction, 2002, 124: 1-17.

1武庆平,姚尚龙.椎管内分娩镇痛进展[J].临床麻醉学杂志,2000,16(11):566-568. 被引量：39
2王宝红,孙金梅,李红梅,姚赛男,赵娜,陈涛,郭艳波.潜伏期穴位按摩联合活跃期椎管内麻醉用于分娩镇痛的效果观察[J].临床合理用药杂志,2015,8(16):119-120. 被引量：3
3王志文,李秀娟.罗哌卡因用于分娩镇痛的观察与护理[J].中华腹部疾病杂志,2004,4(8):594-595.
4鲍静影,陶翠萍,汪洋,高国朋,刘颖,杨齐勤.两种分娩镇痛方法对产妇及新生儿影响的比较观察[J].人民军医,2016,59(11):1167-1168. 被引量：7
5周晓明,岳嘉,常玲,江仁春,许泽会.罗哌卡因在腰—硬联合阻滞分娩镇痛的临床应用[J].贵州医药,2007,31(11):989-990.
6彭桂芳.椎管内分娩镇痛的临床应用进展[J].中国伤残医学,2013,21(1):199-200.
7单菲,伍咏梅,陈延龄.两种镇痛分娩方法对脐动脉血气和乳酸的影响[J].现代诊断与治疗,2016,27(14):2608-2609.
8袁静茹.椎管内分娩镇痛的研究进展[J].河北医药,2006,28(2):137-138. 被引量：4
9黄鑫,陈治君.椎管内分娩镇痛的临床观察[J].中华综合临床医学杂志（北京）,2004,6(12):72-73.
10倪正强.椎管内分娩镇痛的临床进展[J].临床误诊误治,2009,22(5):70-73. 被引量：3

浙江医学

2010年第3期

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