摘要
多发性硬化是中枢神经系统的慢性炎症性脱髓鞘性疾病,其发病机制与免疫调节功能异常密切相关,雌激素具有重要的免疫调节作用,它与多发性硬化的发生,发展与转归关系密切。因此,对雌激素的深入研究可为多发性硬化的治疗提供新的有价值的靶点。
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of central nervous system (CNS) . Its pathogenesis is closely related to the abnormality of immuoregulation. Estrogen has important effect on immunological regulation and closely connects with the genesis, developing, and turnover of multiple sclerosis, Further research of estrogen will provide new targets for the therapy of multiple sclerosis.
出处
《国际免疫学杂志》
CAS
北大核心
2010年第2期141-143,共3页
International Journal of Immunology
关键词
多发性硬化
雌激素
细胞免疫
Multiple sclerosis
Estrogen
Cellular immunity