摘要
目的：建立电感耦合等离子体质谱法测定中药提取物中铅、镉、砷和汞的分析方法。方法：采用高压消解法对样品进行前处理,以↑72Ge、↑115In、↑209Bi作为内标消除非质谱干扰,碰撞反应池消除质谱干扰,采用ICP-MS测定Pb、Cd、As、Hg。结果：方法的线性范围宽,相关系数均〉0.999,检出限为0.001-0.05μg/L,回收率在91.4%-105%,相对标准偏差为0.68%-2.69%,对两种国家标准物质测定,测定值均与真值相吻合。结论：方法精密、准确、可靠,可满足正常来样检测的需要,便于推广。
Objective：To establish a method for determination of lead,cadmium,arsenic and hydrargyrum in chinese traditional medicine extracts by inductively coupled plasma mass spectrometry.Methods：The pretreatment was performed using high-pressure digestion technique,with ↑72Ge,↑115In,↑209Bi as the internal standards to eliminate non-spectroscopic interference and collision reaction cell to eliminate mass spectroscopic interference.ICP-MS was used to determine Pb,Cd,As,Hg.Results：This method had a wide linear range,the linear correlative coefficient for all the elements was higher than 0.999,the detection limit was 0.001-0.05 μg/L,the recovery was at the range of 91.4%-105%,the RSD was 0.68%-2.69%,and the measured values were consisted with the true for national standard reference materials.Conclusion：This method has advantages of high sensitivity and precision and is suitable for various laboratories.
出处
《中国卫生检验杂志》
CAS
2010年第2期272-273,318,共3页
Chinese Journal of Health Laboratory Technology
关键词
ICP-MS
中药提取物
元素
ICP-MS
Chinese traditional medicine extracts
Elements
