摘要
目的:了解我院药品不良反应(ADR)发生的特点及规律。方法:对我院2008年收集到的113例ADR报告,按患者性别、年龄、给药途径、药物剂型、药品种类、ADR累及器官或系统及临床表现等进行分类统计与分析。结果:静脉给药最易引发ADR(59.29%);抗感染药的ADR发生率居首位(46.90%),其次为中药剂制(23.01%)等;临床表现以皮肤及其附件损害最常见(37.17%)。结论:临床应加强和重视ADR监测工作,以减少和避免ADR的发生。
OBJECTIVE： To investigate the characteristics and general pattern of the adverse drug reactions （ADR） occurred in our hospital. METHODS： A total of 113 ADR cases reported by our hospital in 2008 were analyzed statistically in respect of pa- tients＇ age and sex, route of administration, dosage form, category of drug, organs and systems involved in ADR and clinical manifestations, etc. RESULTS： The ADR were mainly induced by venous administration （59.29 % ）. Anti-infective drugs dominated the first place on the list of ADR incidence rate （46.90%） followed by TCM preparations （23.01% ）. The most common manifestation of the ADR was lesion of skin and its appendants （37.17 % ）. CONCLUSION： Great importance should be attached to ADR monitoring to reduce or avoid the occurrence of ADR.
出处
《中国药房》
CAS
CSCD
北大核心
2010年第10期926-927,共2页
China Pharmacy
关键词
药品不良反应
报告
分析
Adverse drug reaction
Report
Analysis
