摘要
目的探讨T2DM对记忆力的影响。方法采用病例对照研究方法 ,用临床记忆量表评价T2DM病例组及对照组的记忆力。结果病例组与对照组的记忆商(MQ)分别为90.0±15.6和100.3±12.8,两组MQ具有统计学差异(P<0.01)。病例组的MQ低于常模均数100(P<0.01),而对照组MQ与常模均数无统计学差异(P>0.05);病例组在五项分测验的年龄量表分均低于年龄、性别、文化程度匹配的对照组(P均<0.01);55岁以下与55岁以上病例组的记忆力均低于对照组。结论 T2DM患者的记忆商降低,其言语记忆和非言语记忆能力均存在不同程度的损害。
Objective To explore the relationship between type 2 diabetes （T2DM） and memory impairment. Methods A frequency matched ease-control study was conducted. 116 T2DM patients were compared with age, gender and education level matched non-diabetic controls（n= 100）. Memory function of the subjects was assessed using Clinical Memory Scale （CMS）. Results The mean memory quotient （MQ） of the case group was significantly lower than that of the control group（90. 0± 15.6 vs 100.3 ± 12.8, P〈0.01）. The mean MQ of the case group was significantly lower than the norm, while no significant difference in MQ was found between control group and the norm（P〉0. 05）. The scores of 5 memory tests from CMS in the case group were all significantly lower than those in the controls, which suggested that the case group had an impaired verbal memory and visuospatial memory. Both age groups （below 55-yr and 55-yr or older group） of the cases had poorer performance in a number of CMS tests compared with the controls, which indicated that the cases in different age groups had an impaired memory function. Conclusions Results from the present study suggest that T2DM is associated with the memory impairment including verbal memory and visuospatial memory.
出处
《中国糖尿病杂志》
CAS
CSCD
北大核心
2010年第3期209-210,共2页
Chinese Journal of Diabetes
