摘要
目的:检测糖尿病(diabetic mellitus,DM)患者糖化血红蛋白(HbA1c)、随机尿微量清蛋白(mAlb)及β2微球蛋白(β2MG)以发现DM早期肾脏损害。方法:血HbA1c、尿mAlb、β2MG均采用免疫比浊法,在雅培AbbottC8000生化分析仪上测定。结果:HbA1c、mAlb、β2MG在尿蛋白阴性组、阳性组患者与对照组之间差异有高度统计学意义(P<0.01)。结论:HbA1c、尿mAlb、β2MG三者联合检测可作为诊断DM早期肾损害可靠而敏感的指标,为监测DM肾病发生及监护治疗的良好实验室指标。
Objective： To detect the level of HbA1c, mAlb and β2MG in patients with DM to find out the early damage of patients with DM. Methods： The level of HbA1c, mAlb and β2MG was measured in Abbott C8000 analyzer by the method of immunoturbidimetry respectively. Results： The differences among the patients with urine protein negative group and ones with urine protein positive group and ordinary healthy control group were significant （P〈0.01）. Conclusion： Blood HbA1c, urine mAlb and β2MG of patients with DM can be reliable and sensitive signals of the early renal damage of DM. They can also be good biochemical markers for monitoring the development of DM and its treatment.
出处
《中国医药导报》
CAS
2010年第9期21-22,共2页
China Medical Herald
