摘要
本实验用放射免疫法研究了必需脂肪酸亚麻酸和亚油酸对BEL-7042人肝癌细胞甲胎蛋白(AFP)的分泌的影响,并观察它们对肝癌细胞生长的抑制作用.实验结果表明,42～50μg/ml亚麻酸能明显地抑制肝癌细胞AFP分泌(P<0.01),亚油酸则作用较弱,与对照相比无差异(P>0.05),我们对亚麻酸的抗癌作用的研究为癌症病人的保健和治疗提供实验依据.
In the present study, the influence of essential free fatty acids on AFP secretion and cell growth of BEL-7402 human hepatocellular cacinoma cell line was investigated by radiommunoassay. The results demonstrated that 40 - 50μg/ ml concentration of linolenic acid could inhibit the AFP secretion obviously( P < 0.01) . The effect of linolenic was weaker than that of linolenic acid and there is no difference between linolenic and contrast ( P > 0.05) . All of these studies about anti-cancer effect of linolenic acid will provide the principle for the patient for health care and therapy.
出处
《中国肿瘤生物治疗杂志》
CAS
CSCD
1998年第4期274-276,共3页
Chinese Journal of Cancer Biotherapy
关键词
必需脂肪酸
肝癌
分泌
甲胎蛋白
essential fatty acid
human hepatocellular carcinoma cell line
AFP secretion
