摘要
目的：探讨血液透析（HD）加血液灌流（HP）对慢性肾衰患者不同分子量物质的清除及临床症状的改善效果。方法：常规HD中于透析器后串联一只50g装灌流器，观察KT／V和TACUrea及血清尿素氛（BUN）肌酐（Cr）、β2微球蛋白（β2－m）下降率及临床症状。结果：与HD相比，HD＋HP治疗期间患者皮肤瘙痒、头痛等发生率减少、程度减轻，心包积液量减少，KT／V有显著意义的增加，TACure符合充分透析标准,BUNCr和β2-m下降率明显高于HD。结论：HD＋HP对尿毒症中小分子物质清除及治疗中的KT／V和CUrea均较理想，能有效改善慢性肾衰患者临床症状，从而提高其生存质量，该方法操作简便，具较高实用价值。
objective: To evaluate the effect of hemodiafiltration with hemoperfusion treating chronicrenal failure. Methods:Post-dialyzer in-line YT-HP/50 hemodilyzer was added to convertional HD, and the reduction rate of BUNCr, β2-m and KT/v,TACurea and the clinical symptoms were observed. Results: With a higher reductionrate of β2-m and Cr,HD+HP had higher KT/v and TACurea reached the standand ofsufficient diafiltration too. The symptoms of patlents were greatly improved. Conclusion: HD with HP is a practical,effective and simple method.
出处
《河北医学》
CAS
1998年第12期1-2,共2页
Hebei Medicine
