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膜联蛋白的研究进展及其在肺纤维化发生机制中的作用 被引量：1

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摘要 膜联蛋白（Annexins）于20世纪70年代末被发现，至今已有30午历史。早期，根据各自的特异功能，它们被赋予了不同的名称。之后，这些蛋白被证明拥有共同的基因序列和结构，在一些关键性质上也有统一性，故而，将其统称为Annexins。此后，不断有新的成员被发现，Annexins家族不断丰富。
作者 蔡浩 倪春辉
机构地区 南京医科大学第一临床医院 公共卫生学院环境卫生与职业卫生学系
出处 《中华劳动卫生职业病杂志》 CAS CSCD 北大核心 2010年第2期144-146,共3页 Chinese Journal of Industrial Hygiene and Occupational Diseases
关键词 膜联蛋白 发生机制 肺纤维化 特异功能 基因序列 统一性
分类号 R686 [医药卫生—骨科学]
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参考文献27

  • 1Gerke V, Moss SE. Annexins: from structure to function. Physiol Rev,2002,82:331-371.
  • 2Marsh D. Peptide models for membrane channels. Biochem J, 1996,315(Pt 2) :345-361.
  • 3Mailliard WS, Haigler HT, Schlaepfer DD. Calcium-dependent binding of S100C to the N-terminal domain of annexin I. J Biol Chem, 1996,271:719-725.
  • 4Rescher U, Gerke V. Annexins-unique membrane binding proteins with diver~e functions. J Cell Sci, 2004,117:2631-2639.
  • 5Diaz-Munoz M, Hamilton SL, Kaetzel MA, et al. Modulation of Ca2+ release channel activity from sarcoplasmic reticulum by annexin VI (67-kDa calcimedin). J Biol Chem, 1990,265:15894-15899.
  • 6Hayes MJ, Moss SE. Annexins and disease. Biochem Biophys Res Commun, 2004,322:1166-1170.
  • 7Franchi F, Viscardi Y, Cetin I, et al. Annexin V C/T-1 polymorphism and pregnancy complications. Haematologica, 2006,91:864.
  • 8Bogdanova N, Horst J, Chlystun M, et al. A common haplotype of the annexin A5 (ANXAS) gene promoter is associated with recurrent pregnancy loss. Hum Mol Genet, 2007,16:573-578.
  • 9de Laat B, Derksen RH, Mackie Ij, et al. Annexin A5 polymorphism (-1C->T) and the presence of anti-annexin A5 antibodies in the antiphospholipid syndrome. Ann Rheum Dis, 2006,65:1468-1472.
  • 10庞宇洁.特发性肺纤维化的发病机制及抗凝治疗研究进展[J].山西职工医学院学报,2009,19(1):80-81. 被引量：4

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同被引文献21

  • 1Nadif R, Jedlicka A, Mintz M, et al. Effect of TNF and LTA poly- morphisms on biological markers of response to oxidative stimuli in coal miners:a model of gene---environment interaction, Tmnour necrosis factor and lymphotoxin alpha. J Med Genet, 2003, 40: 96- 103.
  • 2de Laat B, Derksen RH, Mackie IJ, et al. Annexin A5 polymorphism (-1C→T) and the presence of anti-annexin A5 antibodies in the an- tiphospholipid syndrome. Ann Rheum Dis. 2006,65:1468-1472.
  • 3Gonzalez-Conejero R, Corral J, Roldan VA, et al. A common polymor- phism in the annexin V Kozak sequence (-1C>T)increases transla- tion efficiency and plasma levels of annexin V, and decreases the risk of myocardial infarction in young patients. Blood. 2002,100: 2081-2086.
  • 4Tait JF, Frankenberry DA, Shiang R, et al. Chromosomal localization of the human gene for annexin V (placental anticoagulant protein I) to 4q26-q28. Cytogenet Cell Genet. 1991,57:187-192.
  • 5Grerke V, Moss SE. Annexins :from structure to function. Physiol Rev. 2002,82:331-371.
  • 6Cookson BT, Engelhardt S, Smith C, et al. Organization of the human annexin V (ANX5) gene. Genomics, 1994,20:463 -467.
  • 7Matsuda R, Kaneko N, Horikawa Y, et al. Measurement of urinary annexin V by ELISA and its significance as a new urinary-marker of kidney disease. Clin Chim Acta, 2000,298:29-43.
  • 8Vermes I, Steur EN, Reutelingsperger C, et al. Decreased concentra-tion of annexin V in parkinsonian cerebrospinal fluid: speculation on the underlying cause. Mov Disord, 1999, 14:1008-1010.
  • 9Tzima E, Trotter PJ, Hastings AD, et al. Investigation of the reloca- tion of cytosolic phospholipase A2 and annexin V in activated platelets. Thmmb Res. 2000,97:421-429.
  • 10Tzima E, Trotter PJ, Orchard MA, et al. Annexin V binds to the actin-based cytoskeleton at the plasma membrane of activated platelets. Exp Cell Res, 1999, 251:185-193.

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中华劳动卫生职业病杂志
2010年 第2期

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