摘要
目的系统研究甘肃棘豆的化学成分。方法利用普通硅胶柱色谱对甘肃棘豆乙醇提取物进行化学成分分离,并运用超导核磁(NMR)及高分辨质谱(HR-ESI-MS)等现代波谱技术,结合文献资料的已知化合物波谱数据对分离得到的化合物进行结构鉴定。结果从甘肃棘豆分离并鉴定了13个化合物,分别为鼠李柠檬素(1)、鼠李柠檬素-3-O-β-D-半乳糖苷(2)、鼠李柠檬素-3-O-β-D-半乳糖-4′-O-β-D-葡萄糖苷(3)、(±)-10-甲氧基美迪紫檀素(4)、7β-羟基-β-谷甾醇(5)、7α-羟基-β-谷甾醇(6)、5,11-豆甾二烯-3-醇(7)、β-谷甾醇(8)、β-胡萝卜苷(9)、大豆皂醇B(10)、大豆皂苷Ⅰ(11)、大豆皂苷Ⅱ(12)、DL-3-O-甲基-肌醇(13)。结论以上化合物均为首次从该植物中分离得到。
Objective To study the chemical constituents of Oxytropis kansuensis systematically. Methods Silica gel column chromatographic method was used to isolate and purify the constituents from the extract of O. kansuensis. The structures of the compounds were elucidated by various spectroscopic methods including NMR spectrometer and high resolution mass spectrometry, and the known compounds were identified on the basis of comparing their NMR data with those of corresponding compounds in the literature. Results Thirteen compounds were isolated from O. kansuensis and elucidated as rhamnocitrin （1）, rhamnocitrin-3-O-β-D-galactopyranoside （2）, rhamnocitrin-3-O-β-D-galactopyranoside-4＇-O-β-D-glucuronospyranoside （3）, （-4-）-10-methoxymedicarpin （4）, 7β-hydroxysitosterol （5）, 7α-hydroxysitosterol （6）, 5, 11-stigmastadien-3β-α （7）, β-sitosterol （8）, β-daucosterin （9）, soyasapogenol B （10）, 3-O-[β-D- glucopyranosyl （1-2）-β-D-glucopyranosyt] soyasapogenol B （11）, 3-O-[α-L-rhamn0pyranosyl （1-2）-t3-D- glucopyranosyl （1-2）-β-D-glucopyranosyl] soyasapogenol B （12）, DL-3-O-methyl-inOsitol （13）. Conclusion The compounds are all isolated from this plant for the first time.
出处
《中草药》
CAS
CSCD
北大核心
2010年第2期187-190,共4页
Chinese Traditional and Herbal Drugs
基金
中国科学院重大方向性项目(KGCX2-SW-213-08)
中国科学院"百人计划"资助项目
中国科学院西部之光项目资助
关键词
甘肃棘豆
棘豆属
豆科
Oxytropis kansuensis Bunge
Oxytropis DC.
Leguminosae
