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冠心病患者血清抗心磷脂抗体检测的临床研究

A Clinical Study on Detecting Serum Anticardiolipin Antibody in Coronary Heart Disease
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摘要 为探讨ACA对CHD的临床意义,分别用ELISA和免疫比浊法对34例住院冠心病人和148名健康体检人员的ACA-IgG、ACA-IgM、ACA-IgA和TC、TG、HDL进行了检测。结果CHD组与正常组比较HDL、TC、TG均具显著统计学差异;3类ACA水平与正常组无明显差异,但ACA IgG的消长与血清TG呈正相关(P<0.05);冠心病组的ACA-IgG阳性检出率也明显高于正常组(P<O.O1)。提示血清ACA可能通过影响脂代谢参与了冠心病的发生。因此,血清ACA-IgG的测定对诊断CHD有重要意义。 To research the clinical value of serum ACA, serum ACA-IgG. IgM. IgA. TC. TG. HDL were measured in 34 CHD and 148 health people by ELISA and immune turbidity assay. The results showed that ACA-IgG had a positive association with TG(P<0. 05). The postitive rate of ACA-IgG in CHD group was markely higher than in normal control group(P<0. 01). It is suggested that high level serum ACA-IgG autoantibody have a latent pathogenic effect in CHD forming by influencing lipometabolism. It is important for pognostic and diagnosis of CHD to detect serum ACA-lgG.
出处 《太原科技》 1998年第3期24-25,共2页 Taiyuan Science and Technology
关键词 抗心磷脂抗体 冠心病 甘油三脂 检测 临床研究 antlcardlolipin antibody, coronary heart disease. TO
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  • 1Wang M X,J Immunol,1995年,155卷,1629页
  • 2Gao B,Gene,1993年,126卷,287页

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