摘要
多项研究均证实糖尿病合并高血压的患者，药物治疗确实可以减少大血管和微血管事件。根据循证证据和指南，糖尿病伴高血压患者在生活方式干预的基础上采用肾素血管紧张素系统抑制剂加钙通道阻滞剂或小剂量利尿剂联合降压方案对于降压达标甚为有效。且单粒复方制剂可能更有利于提高治疗依从性而使患者有更多获益。
Overall there is strong evidence that pharmacologic therapy of hypertension in patients with diabetes is effective in producing substantial decrease in macrovaseular and microvascular diseases. According to clinical evidence and guidelines, patients with diabetes mellitus and hypertension should receive drug treatment in addition to lifestyle/behavioral intervention. Combination therapy of rennin-angiotensin system inhibitor with calcium channel blocker or low dose thiazide diuretics is quite efficient to reach the blood pressure target. As considering patient compliance with drug therapy, single pill combination may yield more benefits.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2010年第1期1-5,共5页
Chinese Journal of Endocrinology and Metabolism
关键词
循证医学
糖尿病
高血压
联合治疗
Evidence-based medicine
Diabetes mellitus
Hypertension
Combination therapy
