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2型糖尿病胰岛素抵抗与高脂血症及微血管病变的关系 被引量:30

The Relationship between Insulin Resistance of Diabetes Mellitus Ⅱ and Hyperlipidemia and Micro-vessel Changes
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摘要 目的 :探讨 2型糖尿病的胰岛素抵抗与高脂血症及微血管病变的关系。方法 :通过对 2型糖尿病 16 2例的胰岛素释放试验及 C-肽测量、血脂、微量白蛋白尿的测量和眼底检查方法。结果 :16 2例分为胰岛素分泌缺乏组、高胰岛素分泌组及胰岛素分泌正常范围组 ,而且高脂血症及微血管病变发生率由高到低。结论 :胰岛素抵抗在 2型糖尿病发生发展中起着重要作用 ,而高脂血症是导致胰岛素抵抗的重要因素 ,并最终导致糖尿病并发症发生。 Objective:To explore the relationship between regular insulin resistance and hyperlipidemia,micro-vessel pathological changes.Method:The C-peptide,lipid in blood and micro-protein urine of 162 patients with diabetes mellitus Ⅱ were measured and insulin-releasing test,funduscopy were done.Result:162 patients were divided into low-secreted insulin group,high-secreted insulin group,and normal-secreted insulin group.The occurring rate of hyperlipidemia and micro-vessel pathological changes is from high to low.Conclusion:Regular insulin resistance play a significant function in the patients with diabetes mellitus Ⅱ.Hyperlipidemia is an important factor resulting in regular insulin resistance,and eventually results in diabete complication.
出处 《中国误诊学杂志》 CAS 2004年第3期346-348,共3页 Chinese Journal of Misdiagnostics
关键词 糖尿病血管病变 胰岛索抗药性 高脂血症 Diabetic angiopathies Insulin resistance Hyperlipidemia
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