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不同周期的CAF术前化疗对乳腺癌疗效的观察

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摘要 目的:比较两组不同周期的术前化疗对乳腺癌疗效的影响以及毒性反应。方法:55例局部进展期乳腺癌患者分为两组接受环磷酰胺、阿霉素和5-氟尿嘧啶方案进行术前化疗,对两组的疗效进行比较分析。结果:2周期治疗组总有效率55%,4周期治疗组总有效率85%,两组均无进展病例,4周期组明显优于2周期组,在血液毒性及消化道反应方面两组无显著差异性。结论:CAF方案对局部进展期乳腺癌进行术前化疗,4周期的治疗强度显示出其必要性,是一种安全有效的周期剂量强度,但对4周期治疗的长期生存效果还有待于随访观察和进一步评价。
出处 《长治医学院学报》 2010年第1期34-36,共3页 Journal of Changzhi Medical College
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