摘要
目的:探讨胃肠道间质瘤(GIST)的临床病理特征和预后。方法:对青岛大学医学院附属医院普外科2003年3月-2008年5月收治的70例胃肠道间质瘤患者的临床病理资料进行回顾性分析。结果:单因素及多因素分析显示,肿瘤大小、生长部位、核分裂数和手术方式及术后是否使用甲磺酸依马替尼(Gleevec)辅助治疗均对术后复发有影响。结论:肿瘤部位、肿瘤大小、核分裂相数目、手术方式及甲磺酸依马替尼(Gleevec)辅助治疗是影响胃肠道间质瘤根治术患者预后的重要指标。
Objective： To investigate the clinic and pathologic characteristics and prognostic factors of Gastrointestinal Stromal Tumor （GIST）. Methods： The clinic and pathologic data of 70 patients between March 2003 and May 2008 in Department of General Surgery, the Affiliated Hospital of Medical College of Qingdao University were analyzed retrospectively. Results： Univariate and multivariate analysis indicated that the tumor size,mitotic count, primary location,surgical modality and Gleevec administration postoperatively were related to the prognosis of GIST. Conclusion： Tumor location, tumor size, surgical modality, mitotic count, Gleevec administration postoperatively are important prognostic factors for patients with GIST undergoing radical operation.
出处
《中国现代普通外科进展》
CAS
2009年第12期1062-1065,共4页
Chinese Journal of Current Advances in General Surgery
关键词
胃肠肿瘤·间质瘤·预后
Gastrointestinal tumor·Stromal tumor·Prognosis
