摘要
目的通过比较角膜厚度不同的原发性慢性闭角型青光眼患者的各项分析指标,探讨中央角膜厚度和青光眼严重程度之间的关系。方法将36例患者以中央角膜厚度≥550μm和<550μm分为2组,比较2组患者的视力(最佳矫正视力)、眼压(Goldmann压平眼压计)、视野及垂直杯盘比与中央角膜厚度随时间变化的关系。结果在最佳矫正视力、眼压与中央角膜厚度的生存曲线中,2组患者比较差异均无统计学意义(P=0.1748、0.5410);而视野和垂直杯盘比与中央角膜厚度的生存曲线中,中央角膜厚度≥550μm组患者视野垂直杯盘比平均生存时间分别为(5.71±0.28)a、(3.66±0.56)a,中央角膜厚度<550μm组视野、垂直杯盘比平均生存时间分别为(3.51±0.58)a、(1.43±0.33)a,2组患者比较差异均有显著统计学意义(P=0.0005、0.0030)。结论中央角膜厚度可能成为预测青光眼进展情况的重要指标之一。
Objective To discuss the relationship between central corneal thickness（CCT） and glaucoma severity by comparing the each analyzed index of glaucoma patients with different CCT.Methods Thirty-six glaucoma patients were divided into CCT≥550 μm group and CCT〈550 μm group.The relationship between the best corrected visual acuity,intraocular pressure,visual field data,vertical cup-disc ratios and CCT were compared between two groups with the change of time.Results In analysis of the survival curve of best corrected visual acuity,intraocular pressure and CCT,there was no statistical difference between two groups（P=0.174 8,0.541 0）,but in analysis of the survival curve of visual field data,vertical cup-disc ratios and CCT,the mean survival time of visual field data and vertical cup-disc ratios in CCT≥550 μm group were （5.71±0.28） years and （3.66±0.56） years,which in CCT〈550 μm group were （3.51±0.58） years and （1.43±0.33） years respectively,there were significant differences between two groups（P=0.000 5,0.003 0）.Conclusion CCT may be one of the significant indices in predicting the progression of glaucoma.
出处
《眼科新进展》
CAS
北大核心
2010年第3期259-261,264,共4页
Recent Advances in Ophthalmology
关键词
青光眼
中央角膜厚度
预后
glaucoma
central corneal thickness
prognosis
