摘要
目的探讨窒息新生儿脑血流动力学的状况,以早期诊断脑损伤性疾病。方法应用彩色多普勒超声对40例窒息新生儿和25例正常新生儿的大脑中动脉、大脑前动脉收缩期峰值速度(Vs)、舒张末期速度(Vd)和阻力指数(RI)进行检测。结果轻度窒息新生儿大脑中动脉和大脑前动脉的Vs、Vd均低于正常对照组,RI高于正常对照组(P<0.05)。重度窒息组Vs、Vd明显低于正常对照组,也低于轻度窒息组(P<0.05),RI异常增高;与正常对照组和轻度窒息组比较差异均有统计学意义(均P<0.05)。结论窒息后脑血流动力学改变对判断新生儿有否缺血缺氧性脑病及其程度具有重要的参考价值,有助于脑损伤的诊断和治疗。
Objective To study the changes of cerebrovascular hemodynamics in asphyctic neonate, and to diagnose brain injured disease early. Methods Forty cases of asphyctic neonates and 25 normal neonates （ control group） were enrolled in this study, and the peak velocity in systolic phase （ Vs）, end diastolic velocity （ Vd ） and resistance index （RI） of middle cerebral artery and anterior cerebral artery were measured by color Doppler ultrasound. Results The Vs and Vd of middle cerebral artery and anterior cerebral artery in mild asphyctic neonate group were lower than those in control group, while RI was higher than that in control group （ P 〈 0.05 ）. Vs and Vd in severe asphyctic neonate group were lower than those in control group and mild asphyctic neonate group （ P 〈 0.05 ） , while RI was increased abnormally, there was significant difference among the three groups （ P 〈 0.05）. Conclusion The cerebral heinodynamic changes after asphyxia has important reference value for determining whether there is hypoxic- ischemic encephalopathy （HIE） and its degree, it can improve the diagnosis and treatment of brain injury.
出处
《临床超声医学杂志》
2010年第2期105-107,共3页
Journal of Clinical Ultrasound in Medicine
关键词
窒息
新生儿
超声检查
多普勒
彩色
缺血缺氧性脑病
Asphyctic, neonate
Uhrasonography, Doppler, color
hypoxic - ischemic encephalopathy
