摘要
阴离子交换蛋白(anion exchanger,AE)2在正常人体多重组织中表达,是一种多功能嵌膜蛋白,最初在红细胞膜上被鉴定。其主要功能是转运一价阴离子,生理条件下以极快速率进行Cl-/HCO3-交换。近年来发现其在某些肿瘤中表达明显异常,可能与肿瘤的发生、发展密切相关,并可能成为肿瘤疫苗治疗的重要靶位。
Anion exchanger （AE）2 expressed on many tissue of human beings. It is a versatile embedded membrane proteins, and was identified on the red blood cell membrane initially. The main function of anion exchanger 2 is to transfer anion of one price, and to exchange CI /HCOa quickly under physiological conditions. In recent years, abnormal expressions of anion exchanger 2 on some tumors were found, and it may be closely related to the occurrence and development of tumors, and may become an important target site of tumor vaccine therapy.
出处
《中华妇幼临床医学杂志（电子版）》
CAS
2010年第1期65-67,共3页
Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition)
