摘要
目的探索2型糖尿病的方-症-证三者之间的关系。方法以9家医院的2501例回顾性2型糖尿病病例的临床数据为基础,运用关联规则的方法分析方-症-证之间的关联关系。结果从122首方剂中选取生脉饮、六味地黄汤、四君子汤等3首方剂分析用药患者症状间的关系,服用生脉饮的患者倦怠乏力、口干口渴、溲频尿多、肢体麻木、视物模糊、口渴欲饮、夜尿频多、气短懒言等症状出现的频率较高,服用六味地黄汤的患者倦怠乏力、口渴欲饮、视物模糊、夜尿频多、口干口渴、肢体麻木、气短懒言、腰膝酸软等症状出现的频率较高,且这些症状之间存在多重相关的关联关系。服用四君子汤的患者中,倦怠乏力、腰膝酸软、夜尿频多、气短懒言、肢体麻木、失眠、视物模糊等症状出现的频率较高,且这些症状之间存在多重相关的关联关系。结论关联规则可以分析2型糖尿病的方证关系,能探索症状间的多重相关关系。
Objective To explore the relationship among the disease - syndrome - formula of type 2 diabetes. Methods Based on the clinical data of 2 501 cases of type 2 diabetes, to study the relationship among the disease - syndrome - formula of type 2 diabetes by making use of association rules. Results Three formulas, Shengmai Yin （Pulse-activating Fluid）, Liuwei Dihuang Decoction （Decoction of Six Herbs Including Rehmannia）, and Sijunzi Decoction （Decoction of Four Noble Herbs）, were selected from 122 ones to analyze the relationship between the formula and symptoms. The occurrence of fatigue with weakness, dry mouth with thirst, frequent urination with increased volume of urine, numbness of limbs, blurred vision, thirst with preference of drinking water, frequent nocturnal urination, and shortness of breath with inactive talking was in high frequency in those patients who were prescribed Shengmai Yin. The occurrence of fatigue with weakness, thirst with preference of drinking water, blurred vision, frequent nocturnal urination, dry mouth with thirst, numbness of limbs, shortness of breath with inactive talking, and soreness and weakness of lumbus and legs was in high frequency in those patients prescribed Liuwei Dihuang Decoction, and there existed a multi-association among these symptoms. The occurrence of fatigue with weakness, soreness and weakness of lumbus and legs, frequent nocturnal urination, shortness of breath with inactive talking, numbness of limbs, insomnia, and blurred vision was in high frequency in those patients who were prescribed Sijunzi Decoction, and there existed a multi-association among these symptoms. Conclusion The association rule can be adopted to analyze the relationship between formula and syndrome, and to explore the multi-association relationship among the symptoms of type 2 diabetes.
出处
《中医杂志》
CSCD
北大核心
2010年第1期64-67,共4页
Journal of Traditional Chinese Medicine
基金
国家自然科学基金资助项目(90209012)
科技部科技基础工作专项基金资助项目(2001Dea20010)
关键词
2型糖尿病
证候
关联规则
症状
中医药疗法
Type 2 Diabetes
TCM syndromes
Association rule
Symptoms
TCM therapy
