摘要
本文检测３１９７例儿科常见疾病患儿的尿ＮＡＧ及肌酐（ｃｒｅａｔｉｎｉｎｅ，Ｃｒｅ），并与３０例健康儿童进行对照。结果显示：正常对照组尿ＮＡＧ为１０．９±５．１１ｇ／Ｌ，在未考虑尿流量对ＮＡＧ影响时，各种疾病患儿尿ＮＡＧ比正常儿均升高，其中呼吸系统疾病、急性肠炎患儿尿ＮＡＧ升高有显著性差异，急性肾炎、肾病综合征及传染病患儿尿ＮＡＧ升高有高度显著性差异，余无意义。为减少尿流量对ＮＡＧ影响，用酶活性与尿肌酐比值ＮＡＧ／Ｃｒｅ（ｕ／ｇ·ｃｒｅ）表示酶活性时，所有疾病患儿尿ＮＡＧ均高于正常对照组，均有高度显著性差异。作者建议对住院及门诊病儿常规进行无损伤的尿ＮＡＧ检查，可以监测肾功能的变化。
Urine N acetyl β- glucosminidase(NAG) and creatinine(Cre) of 179 common pediatrics cases were detectded in this essay, and compared with 30 healthy children. The result displayed that urine NAG was 10 9±5 11 g/l in normal comparable group and which was higher in various of children'patients without considering the influence of urine flow. There was remarkable difference in the raising of urine NAG in respiratory system diseases and active enteritis patients, higher remarkable difference in nephritis kidney disease syndrome and communicable disease patients, no significance in ofhers. In order to decrease the influence of the urine flow, the enzyme activity was expressed as the ratio of NAG to urine creatine (unit:u/g.cr) which was higher in all kinds of diseases in children than in normal constrast group, there was high remarkable difference.
出处
《中国优生与遗传杂志》
1998年第4期29-30,共2页
Chinese Journal of Birth Health & Heredity
