摘要
为探讨生长抑素（somatostatin）治疗重症急性胰腺炎（SAP）的临床疗效。我院1996年8月至1997年8月非手术治疗33例SAP患者，除传统非手术治疗外，常规应用生长抑素（治疗组n=33）。与1996年8月前非手术治疗SAP患者比较（对照组n=29）。两组病例年龄、病程、病情基本一致。结果，治疗组全身及腹部症状、体征迅速减轻，胃肠减压量显著低于对照组（P＜0．005）。血淀粉酶下降时间快，并发症少（P＜0．005）。说明生长抑素（施他宁）是一种较好的胃肠液、胰液、胰酶分泌抑制剂。在SAP早期应用，能迅速控制病情，缩短住院时间，提高治愈率。
To explore the curative effect of somatostatin (stilamin)in the treatment of severe acutepancreatitis (SAP), 33 patients with SAP were treated with the application of somatostatin (treatmentgroup, n=33) from August 1996 to August 1997, the convientional non-operative methods were used aswell. In comparison with the patients treated with non-operative procedure before August 1996 (contrastgroup, n=29), there were no difference in age, curse of disease and clinical appearance between twogroups. The result showed a rapid improvement of general condition and abdominal symptoms and signs,redaction of serum amylase level in a shorter time, and fewer complications (P＜O. 005). The amount ofgastroenteric decompression in treatemnt group was less than that in contrast group (P＜0. 005). It showsthat somatostatin is a good inhibitor to pancreatic and gastointestinal secetion. Application of somatostatinon the early stage of SAP may improve the disease rapidly, reduce the duration of hospitalization and increase cure rate.
出处
《临床外科杂志》
1998年第4期203-204,共2页
Journal of Clinical Surgery
