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bFGF、ET-1在正常皮肤中的表达 被引量:2

Expression of bFGF and ET-1 in normal human skin
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摘要 目的;为了探讨角朊细胞在体内是否表达bFGF、ET-1。方法:采用了免疫组织化学的方法检测了正常皮肤用朊细胞及皮肤中其它细胞bFGF、ET-1表达情况。结果:体内角朊细胞及皮肤中一些其它细胞均有bFGF、ET-1表达。结论:体内角朊细胞可能通过bFGF、ET-1等因子影响黑素细胞的生长分化。 In oroer to investigate whether keratinocytes express bFGF and ET-1 in vivo. Method We detected the expression of bFGF and ET-1 in normal human skin using the method of immunohistochemistry.Results Keratinocytes and some other cells in normal human skin expressed bFGF and ET-1. Conlusion Keratinocytes may infiuence the growth and differentiation of melanocytes via bFGF and ET-1 in vivo.
出处 《中国皮肤性病学杂志》 CAS 北大核心 1998年第4期203-204,共2页 The Chinese Journal of Dermatovenereology
关键词 角朊细胞 黑素细胞 皮肤 BFGF ET-1 Keratinocyte Fibroblast growth factor, basic Endothelin-1
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  • 1Milker SJ.Biology of basal cell carcinoma(part I).J Am Acad Dermatol 1991;24:161-175.
  • 2Oh CK,Kwon YW,Kim YS,et al.Expression of basic fibroblast growth factor,vascular endothelial growth factor.and throm-bospondin-1 related to microvessel density in nonaggressive and aggressive basal cell carcinoma.J Dermatol 2003;30:306-313.
  • 3Halaban R,Kwon BS,Ghosh S,et al.bFGF as an autocrine growth factor for human melanomas.Oncogen Res 1988;3:177-186.
  • 4Arbiser JL,Byers HR,Cohen C,et al.Altered basic fibroblast growth factor expression in common epidermal neoplasms:Examination with in situ hybridization and immunohistochemistry.J Am Acad Dermatol 2000;42:973-977.
  • 5Czubayko F,Liaudet-Coopman ED,Aigner A,et al.A secreted FGF-binding protein an serve as the angiogenic switch in human cancer.Nat-Med 1997;3:1137-1140.
  • 6Schulze-Osthoff K,Risau W,Vollmer E,et al.In situ detection of basic fibroblast growth factor by highly specific antibodies.Am J Pathol 1990:137;85-92.
  • 7Grimme HU,Termmer CC,Bennett KL,et al.Colocalization of basic fibroblast growth factor and CD44 isoforms containing the variably spliced exon V3(CD44v3)in normal skin and in epidermal skin cancers.Br J Dermatol 1999;141:824-832.
  • 8Botchkarev VA,Metz M,Botchkareva NV,et al.Brain-derived neurotrophic factor,neurotrophin-3 and neurotrophin-4 act as "epitheliotrophins"in murine skin.Lab Invest 1999;79:557-572.
  • 9Pincelli C,Marconi A.Autocrine nerve growth factor in human keratinocytes.J Dermatol Sci 2000;22:71-79.
  • 10Pincelli C,Haake AR,Benassi L,et al.Autocrine nerve growth factor protects human keratinocytes from apoptosis through its high-affinity receptor(TRK):a role for BCL-2.J Invest Dermatol 1997:107:757-764.

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