1Gassmann M,Chilov D,Wenger RH. Regulation of the hypxia - inducible factor - 1 alpha. ARNT is not necessary for hypoxic induction of HIF - 1 alpha in the nucleus. Adv Exp Med Biol, 2000,475 : 87 - 99.
2Bruick PK, Mcknight SL. Transcription Oxygen sensing gets a second wind. Science, 2002,295 ( 5556 ) : 807 - 808.
3Linden T, Katschinski DM, Eckhardt K, et al. The antimycotic ciclopiroxo lamine Induces HIF- 1α stability, VEGF expression, and angiogenesis. FASEB J, 2003,17 (2) : 761 - 763.
5Hartsfield CL, Alam J, Chio AM. Differential signaling pathways of HO- I gencexpression in pulmonary and systemic vascular cells. Am J Physiol, 1999,277(61 ) : L1113 - L1114.
6Zheng JZ, Leung SW. Transactivation and inhibitory domains of Hypoxia- inducible factor lalpha. Modulation of transcriptional activity by oxygen tension. Biol Chem, 1997,272 ( 31 ) : 19253- 19260.
7Bernhardt WM, Schmitt R, Rcxsenberger C, et al. Exprexsion of hypoxia- inducible transcription factors in developing human and rat Ridneys. Kidney Int, 2006,69 ( 1 ) : 114 - 122.
2[1]Stroka DM, Burkhardt T, Desbaillets I , et al . HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia. FASEB J, 2001 , 15(13):2445-2453.
3[2]Semenza GL, Roth PH, Fang HM, et al. Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1. J Biol Chem, 1994, 269(38):23757-23763.
4[3]Forsythe JA, Jiang BH, Iyer NV, et al . Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol Cell Biol, 1996, 16(9):4604-4613.
5[4]Suter GH, Laughner E, Semenza GL. Hypoxia-inducible factor 1protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missence mutations. Proc Natl Acad Sci USA , 2000, 97(9):4748-4753.
6[5]Sun X, Kanwar JR, Leung E, et al .Gene transfer of antisense hypoxia-inducible factor 1 alpha enhances the therapeutic efficacy of cancer immunotherapy. Gene Ther , 2001,8(8):638-645.
7[6]Isaac DD, Andrew DJ. Tubulogenesis in Drosophila: a requirement for the trachealess gene product. Genes Dev, 1996 ,10(1):103-117.
8[7]Kallio PJ, Pongratz I, Gradin K, et al. Activation of hypoxia-inducible factor 1 alpha: posttranscriptional regulation and conformational change by recruitment of the ARNT transcription factor. Proc Natl Acad Sci U S A, 1997, 94(11):5667-5672.
9[8]Pugh CW, O'Rourke JF, Nagao M, et al. Activation of hypoxia-inducible factor-1; definition of regulatory domains within the alpha subunit. J Biol Chem, 1997, 272(17):11205-11214.
10[9]Semenza GL. Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. Annu Rev Cell Dev Biol, 1999, 15:551-578 .
2Fine LG,Bandyopadhay D,Norman JT.Is there a common mechanism for the progression of different types of renal diseases other than proteinuria? Towards the unifying theme of chronic hypoxia.Kidney Int,2000,57(Suppl 75):s22-s26.
3Donnelly R,Emslie-Smith AM,Gardner ID,et al.Vascular complications of diabetes.BMJ,2000,320(7241):1062-1066.
4Hirota K.Hypoxia-inducible factor 1-α master transcription factor of cellular hypoxic gene expression.Journal of Anesthesia,2002,16(2):150-159.
5Semema G.Signal transduction to hypoxia inducible factor-1.Biochem Pharmacol,2002,64(5-6):993-998.
6Taille C,EI-Benna J,Lanone S,et al.Induction of heme oxygenase-1 inhibits NADPH oxidase activity by down-regulating cytochrome b558 expression via.The reduction of heme availbaility.Biol Chem,2004,279(27):28681-28688.
7Seligson D,Janzen N,Yu H,et al.Using tumor markers to predict thesurvival of patients with metastatic renal cell carcinoma[J].J Urol,2005,173(5):1496-1501.