摘要
通过氯甲基化反应,将冠醚二苯并-18-冠-6(DBC)转变为氯甲基化的冠醚(CMDBC),使交联聚乙烯醇(CPVA)微球表面的羟基与CMDBC之间发生亲核取代反应,从而实现冠醚的固载化,制得了固载有冠醚的功能微球DBC-CPVA。在建立了冠醚DBC固载量测定方法(溴百里香酚蓝-固相萃取法)的基础上,重点研究了主要因素对DBC固载化过程的影响规律。结果表明:反应温度与溶剂性质对DBC在CPVA微球上的固载化反应有较大的影响,在70℃极性较强的N,N-二甲基甲酰胺(DMF)溶剂中,可制得冠醚DBC固载量为1.72 mmol/g的DBC-CPVA功能微球。
Crown ether dibenzo-18-crown-6 （DBC） was chloromethylated using 1,4-bis （chloromethoxy） butane （BCMB） as chloromethylation reagent. DBC was transferred into chloromethylated crown ether CMDBC. The nucleophilic substitution between chloromethyl groups of CMDBC and the hydroxyl groups of crosslinked polyvinyl alcohol （CPVA） microspheres was carried out, and immobilization of DBC on CPVA microspheres was realized, resulting in functional microspheres DBC-CPVA. Based on seting up the method to determine the immobilization amount of DBC, bromothymol blue-solid extraction method, effects of main factors on the immobilization reaction were mainly investigated. Results show that the reaction temperature and solvent polarity affect the immobilization reaction greatly, and the microspheres DBCCPVA with a DBC immobilization amount of 1.72 mmol/g can be obtained at 70℃ and in DFM solvent with stronger polarity.
出处
《功能高分子学报》
CAS
CSCD
北大核心
2009年第4期343-348,共6页
Journal of Functional Polymers
基金
山西省自然科学基金(2008021013)
关键词
二苯并-18-冠-6
氯甲基化
交联聚乙烯醇微球
固载化
钾离子
dibenzo-18-crown-6
chloromethylation
crosslinked polyvinyl alcohol microsphere
immobilization
（potassium） ion
