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弥可保对奥沙利铂神经毒性的防治效果观察 被引量:4

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摘要 目的评价弥可保对奥沙利铂神经毒性的防治效果。方法对103例应用5-Fu、CF及奥沙利铂联合化疗病人随机分为两组,预防组于第1天化疗开始前予以弥可保针剂0.5mg静脉推注,连续3~5d,观察神经毒性的发生率。结果预防组奥沙利铂神经毒性发生率为30.8%(16/52),对照组82.4%(42/51),经χ2检验,差异有显著性(P<0.01)。结论弥可保对预防奥沙利铂的神经毒性有较好的治疗效果,值得临床推广。
出处 《中国现代医生》 2009年第35期57-57,82,共2页 China Modern Doctor
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