摘要
目的:观察静脉泵入与静脉注射速尿治疗中重度充血性心力衰竭(CHF)的临床效果。方法:86例CHF患者被随机分为静脉泵入组与静脉注射组,各43例。两组均给予心衰的基础治疗,静脉泵入组速尿100mg/d,20mg/h持续静脉泵入5h,静脉注射组100mg/d,1次静注。共观察7d,治疗前后测体重、左室射血分数(LVEF)、心输出量(CO)、6min步行距离。结果:静脉泵入组总有效率为88.4%,静脉注射组的79.1%,差异有显著性(P<0.05)。静脉泵入组体重、LVEF、CO、6min步行距离改善明显优于静脉注射组(P<0.05)。结论:静脉泵入速尿治疗CHF的疗效优于静脉注射。
Objective： To observe the clinical efficacy of intravenous pumping and intravenous injection of furosemide on moderate and severe congestive heart failure （CHF）. Methods： A total of 86 cases of CHF patients were randomly average divided into intravenous pumping group （43 cases）, and intravenous injection group （43 cases）. Both groups were given the basic treatment of heart failure. Beside this, the former group was given 100 mg/d furosemide by intravenous pumping at a rate of 20 mg/h continuous 5 h, and the latter one was given 100 mg/d furosemide by one intravenous injection. The observation lasted 7 days. Body weight, left ventrieular ejection fraction （LVEF）, cardiac output （CO）, and 6--min walking distance was measured before and after treatment. Results.. The total effective rate in the intravenous pumping group and the intravenous injection group was 88.4% and 79.1 %, respectively, it difference was statistically significant （P〈0.05） . The improvement degree of body weight, LVEF, CO, and 6--min walking distance of intravenous pumping group was significantly better than those of intravenous injection group （P〈0. 05）. Conclusion： The efficacy of intravenous pumping of furosemide is more effective than intravenous injection in treatment of CHF.
出处
《心血管康复医学杂志》
CAS
2009年第6期572-574,共3页
Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词
呋塞米
心力衰竭
充血性
输注
静脉内
Furosemide
Heart failure, congestive
Infusions, intravenous
