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多巴胺、地高辛、ACEI、呋塞米联合用治疗难治性心衰21例疗效观察 被引量:4

Dopamine,Digoxin,ACEI and Furosemide were Jointly Applied to Refractory Heart Failure
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摘要 目的总结多巴胺、地高辛、ACEI、呋塞米合用治疗难治性心力衰竭的价值.方法对21例难治性心衰(心功能Ⅲ级9例,Ⅳ级12例)采用多巴胺静滴,地高辛、卡托普利或依那普利口服,呋塞米静注5~7 d,观察心功能、心脏每搏排出量(SV)、射血分数(EF)、心脏指数(CI)、心肌耗氧量变化情况.结果显效12例(57.1%),有效7例(33.3%),无效2例(9.6%);EF,SV,CI治疗后均较治疗前显著提高(P<0.01);心肌耗氧量治疗后较治疗前明显降低(P<0.01).结论多巴胺、地高辛、ACEI、呋塞米合用治疗难治性心力衰竭,疗效佳、安全. Objective To summarize the value of dopamine, digoxin, angiotesin converting enzyme inhibitor (ACEI) and furosemide in the treatment of refractory heart failure. Methods Twenty-one patients with refractory heart failure were treated with dopamine ( intravenous drip) , oral digoxin, captopril or enalapril and intravenous fumsemide for 5 -7 days. Then, the changes in heart function, stroke volume (SV) , ejection fraction (EF), cardiac index (CI) and myocardial oxygen consumption were observed. Resuits Of the21 patients, 12 (57.1%) achieved obvious effect, seven (33.3%) achieved ordinary effect and two (9.6%) achieved no effect. The parameters after treatment such as EF, SV and CI rose significantly, and myocardial oxygen consumption went down significantly (P 〈 0.01 ). Conclusion Joint dopamine, digoxin, ACEI and furosemide are effective on refractory heart failure.
出处 《临床军医杂志》 CAS 2005年第6期732-733,共2页 Clinical Journal of Medical Officers
关键词 难治性心力衰竭 多巴胺 联合用药 地高辛 ACEI 呋塞米 refractory heart failure dopamine joint application
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