摘要
目的探讨短暂性脑缺血发作患者的焦虑、抑郁及社会支持情况对其睡眠的影响。方法在151例短暂性脑缺血发作患者中,应用自评焦虑量表(SAS)、自评抑郁量表(SDS)、社会支持评定量表(SSRS)及匹兹堡睡眠指数(PSQI)评估他们的焦虑、抑郁、社会支持和睡眠情况,分析其相关性及前三者对睡眠的影响。对短暂性脑缺血发作进行4周内科治疗的同时,对伴有焦虑或(和)抑郁症状的给予帕罗西汀治疗,并评估治疗对睡眠质量影响。结果151名患者中单独出现焦虑、抑郁症状的机率分别为33.8%、17.2%,二者共存的发生率为9.9%;存在睡眠障碍的(PSQI>7)占67.5%。PSQI与SAS、SDS、主观支持、对支持的利用得分均存在相关性(γ=0.68、0.52、-0.40、-0.39,P<0.05),有统计学意义。多因素回归分析发现:SAS、SDS、主观支持、对支持的利用度均可影响睡眠质量。Logistic回归分析发现:治疗后发作次数、SAS、SDS的减少和对支持的利用度增加有利于睡眠障碍的改善(OR=0.214、2.350、1.946、0.318,P<0.05)。结论短暂性脑缺血发作患者存在较广泛的睡眠障碍,焦虑、抑郁和社会支持可能与睡眠障碍相关,改善焦虑、抑郁症状可能有利于睡眠质量的提高。
Objective To explore effects of anxiety, depression and social support on sleep quality in patients with transient ischemic attack. Methods A total of 151 patients with transient ischemic affack were assessed with Self Anxiety Scale(SAS), Self Depression Scale (SDS), Social Support Review Scale(SSRS) and Pittsburgh Sleep Quality Index. After 4 - week integrative treatment including therapy of anxiety and depression, the efficaty was evaluated. Results The occurrence rate of anxiety symptom only was 33.8%, the rate of depression was 17.2%, and the rate of both symptoms was 9.9%. There were 67.5% of total patients with sleep disorder. The score of PSQI had significant correlation with scones of SAS, SDS, subjective support and utilization of support quality ( r = 0.68,0.52, - 0.40, - 0.39, P 〈 0.05). Anxiety, depression, subjective support and utilization of support affected sleep quality. Smaller times of ischemic attack, lower score of SAS and SDS, higher utilization of support were found to benefit sleep quality. Conclusion There would have high prevalence of sleep disorder in patients with transient ischemic attack. Anxiety, depression and social support could affect sleep quality.
出处
《精神医学杂志》
2009年第6期420-422,共3页
Journal of Psychiatry
关键词
短暂性脑缺血发作
焦虑
抑郁
社会支持
睡眠质量
Transient ischemic attack Anxiety Depression Social support Sleep quality