期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

乳源抗高血压活性肽作用机理及构效关系研究进展

Progress on the Antihypertensive Mechanism and Structure Activity Relationship of Antihypertensive Peptides Derived from Milk Protein
暂未订购
导出
摘要 乳源抗高血压活性肽以其安全性、无副作用和良好降压效果,日益成为研究热点。文章主要综述了乳源抗高血压活性肽的降压作用机理,并对其构效关系进行分析,展望其开发应用状况和发展前景,旨在为更好地利用乳源蛋白资源开发降血压活性肽提供一定的理论依据及参考。 Antihypertensive peptides have security,avirulence and the distinct effect of depressed blood pressure.In this paper,antihypertensive mechanism and structure activity relationship of antihypertensive peptides derived from milk protein were mainly summarized.The research and application were introduced.
作者 宫霞
机构地区 上海商学院食品学院
出处 《乳业科学与技术》 2009年第6期294-298,共5页 JOURNAL OF DAIRY SCIENCE AND TECHNOLOGY
基金 上海市教委创新项目(09YZ470)
关键词 抗高血压活性肽 血管紧张素转化酶 机理 构效关系 antihypertensive peptides angitensin-converting enzyme mechanism structure activity relationship
分类号 R151 [医药卫生—营养与食品卫生学]
  • 相关文献

参考文献25

  • 1段涛,叶磊.降血压肽的研究及应用前景[J].江苏食品与发酵,2008(4):14-17. 被引量：9
  • 2Turner A J, Hooper N M. The angiotensin-convertingenzyme gene family; genomies and pharmacology. [J]. Trends Pbarmeol. Sei., 2002, 23:177-183.
  • 3Arihara K,Nakashima Y, Mukai T,et al. Peptide inhihitors for angiotensin I-convening enzyme from enzymatic hydrolysates of porcine skeletal muscle proteins [J]. Meat Science, 2001,57: 319-324.
  • 4Conlin P R. Efficacy and safety of angiotensin receptor blockers:A review of Losartan in essential hypertension [J]. Current Ther. Res., 2001, 62: 79-91.
  • 5Richard J, FitzGerald Brian A, et al. Hypotensive peptides from milk protenis [J]. American Society for Nutritional Science, 2004, 4:980s-988s.
  • 6Ehlers R W & Riordan J F. Angiotensin-converting enzyme:new concepts concerning its biological role [J]. Biochemistry, 1989, 28:5311-5318.
  • 7Schror K. Role of prostaglandins in the cardiovascular effectsof bradykinin and angiotensin converting enzyme inhibitors [J]. J. Cardio. Pharm., 1992, 20:568-573.
  • 8Husain A. The chymase-angiotensin system in humans [J].J. Hyper, 1993, 11: 1155-1159.
  • 9Weber M A. Vasopepfidase inhibitors [J]. The Lancet, 2001, 358: 1525-1532.
  • 10Yangisawa M,Kufihara H,Kimura S,et al. A development vascor strict or peptide by vascular endothelial cells[J]. Nature, 1988, 332:411-415.

二级参考文献33

  • 1林汝法,陕方,宋金翠,孟宪军.酶法水解苦荞麸皮蛋白生产降血压肽[J].食品科学,2004,25(11):207-209. 被引量：16
  • 2卞则梁,王光辉.质谱与生命科学[J].化学通报,1994(7):40-46. 被引量：6
  • 3戴军,谢广发,陈尚卫,帅桂兰,顾小红,赵光螯.绍兴黄酒中一种ACE活性抑制肽的分离和鉴定[J].食品与发酵工业,2005,31(5):98-101. 被引量：30
  • 4Ichimura Toshiaki, Hu Jianen, Aita Duong Qua, et al. Angiotensin Ⅰ-Converting Enzyme Inhibitory Activity and Insulin Secretion Stimulative Activity of Fermented Fish Sauce[J].Journal of Bioscience and Bioengineering, 2003,96(5): 496-499.
  • 5Blanca Hern'andez-Ledesma, Lourdes Amigo, Mercedes Ramos, et al. Application of high-performance liquid chromatography tandem mass spectrometry to the identification of biologically active peptides produced by milk fermentation and simulated gastrointestinal digestion [J].Journal of Chromatography A, 2004, 1049:107-114.
  • 6Danny Avan Elswijk, Otto Diefenbach, Sonja van der Berg, et al. Rapid detection and identification of angiotensin-converting enzyme inhibitors by on-line liquid chromatography-biochemical detection, coupled to electrospray mass spectrometry[J].Journal of Chromatography A, 2003,1020:45-58.
  • 7Jose angel Gomez-Ruiz, Mercedes Ramos, Isidra Recio. Identification and formation of angiotensin-converting enzyme-inhibitory peptides in Manchego cheese by high-performance liquid chromatography tandem mass spectrometry [J].Journal of Chromatography A, 2004, 1054:269-277.
  • 8Muguerza B, Ramos M. Antihypertensive activity of milk fermented by Enterococcus faecalis strains isolated from raw milk[Jj.International Dairy Journal, 2006, 16(1):61-69.
  • 9Vanessa Vermeirssen, Arie van der Bent, John Van Camp,et al. A quantitative in silico analysis calculates the angiotensin Ⅰ converting enzyme (ACE) inhibitory activity in pea and whey protein digests [J].Biochimie, 2004,86:231-239.
  • 10Jang A, Lee M. Purification and identification of angiotensin converting enzyme inhibitory peptides from beef hydrolysates[ J ].Meat Science, 2005,69: 653-661.

共引文献9

乳业科学与技术
2009年 第6期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部