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七氟醚和丙泊酚应用于神经外科手术麻醉的比较研究 被引量:8

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摘要 目的比较七氟醚、丙泊酚维持麻醉状态下神经外科鞍区占位手术患者颅内压、脑氧代谢和相关临床指标,指导麻醉方法的选择。方法81例ASAⅠ-Ⅱ鞍区占位择期手术患者随机分为S组和P组,分别采用七氟醚和丙泊酚维持麻醉。记录两组麻醉诱导后颅内压(ICP)、血流动力学指标、术毕睁眼和拔管时间及不同时间脑氧代谢指标颈内静脉血氧饱和度(SjvO2)水平,计算颈内动静脉氧差(AdjO2)。结果两组患者术毕睁眼时间和拔管时间无差异;在诱导后40min,P组ICP低于S组且低于P组诱导后5min;SjvO2在S组T2、T3和T4时点明显升高,AdjO2明显降低。结论在合理用药的前提下,七氟醚和丙泊酚均适用于神经外科手术。
作者 孟春 张彦
机构地区 天津市环湖医院
出处 《山东医药》 CAS 北大核心 2009年第48期69-71,共3页 Shandong Medical Journal
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