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胰岛素加维生素C对SAH后CVS的疗效观察 被引量：1

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摘要 目的初步探讨胰岛素加维生素C对蛛网膜下腔出血(SAH)后脑血管痉挛(CVS)的作用。方法我院2000年至2006年蛛网膜下腔出血病人共173例,其中外伤性的83例,高血压性的52例,自发性的38例,都有头晕、头痛、恶心呕吐等症状,随机分为三组:SAH组(50例)、SAH+胰岛素组(60例)、SAH+维生素C+胰岛素组(63例)。结果临床疗效观察可知,维生素C+胰岛素治疗可明显缩短蛛网膜下腔出血患者头晕、头痛、恶心呕吐等症状发作的时间。血管内皮细胞胰岛素受体在SAH组和单独应用胰岛素治疗组表达明显下调,而胰岛素和维生素C联合应用显著增加胰岛素受体的表达。结论维生素C和胰岛素联合运用可有效缓解患者SAH后的脑血管痉挛,明显缩短蛛网膜下腔出血患者头晕、头痛、恶心呕吐等症状发作的时间,既缩短了病程,也降低了死亡率,同时还减少了合并症和后遗症的发生。而单独应用胰岛素未能缓解血管痉挛。
作者 黄杨效 卢洁云
机构地区 东莞市东坑医院
出处 《国际医药卫生导报》 2009年第24期44-45,共2页 International Medicine and Health Guidance News
关键词 蛛网膜下腔出血 血管痉挛 胰岛素 维生素C
分类号 R743.3 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献9

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二级参考文献24

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国际医药卫生导报
2009年 第24期

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