摘要
目的探讨小儿神经母细胞瘤伴骨转移的生物学行为特点。方法对１０例误诊、误治的小儿神经母细胞瘤伴骨转移的临床病理资料进行认真复习，并观察其组织学特点。结果神经母细胞瘤的骨转移多见于三岁以上的幼儿；转移部位多见于颅顶骨和胫骨；组织学类型为分化较差的神经母细胞瘤。结论神经母细胞瘤的骨转移是本病的晚期表现，预后极差。
Objective To study the biologic behaviors of bone metastatic neuroblastoma in Children.Mehthod The clinico-pathological data of 10 children patients with bone metastatic neuroblastoma who were misdiagnosed and mistreated were restudied and their biologic behaviors were observed. Results Bone metastatic neuroblastoma was more common in children over 3 years old which was poorly differentiated type according to histologic classification.Conclusion Bone metastasis of neuroblastoma is the manifestation of an advanced stage and its prognosis is very poor.
出处
《泰山医学院学报》
CAS
1998年第3期200-202,共3页
Journal of Taishan Medical College
关键词
神经母细胞瘤
骨转移
病理变化
neuroblastoma
bone metastasic
chinical characteristic
pathological changes
