摘要
选用选择性动脉导管化疗替代口服和静脉注射全身化疗治疗直肠癌根治术后患者56例,靶动脉为肠系膜上动脉,左(右)髂内动脉和肝固有动脉.化疗药物为DDP 60～80mg,5-Fu 1000～1500 mg,MMC 8～10 mg.经过5年以上的随访,结果复发和转移18例,死亡16例,带瘤生存2例,其1、2、3、4、5年的生存率分别为94.6%、85.7%、82.1%、78.6%、71.4%.治疗时无大出血、肠坏死、死亡等严重并发症.结果显示选择性动脉导管化疗可明显提高直肠癌根治术后患者的5年生存率,降低肿瘤的复发和转移率,且副作用少,可替代口服和静脉注射全身化疗.
There are 56 cases of rectal cancer after radical operation, which were treated by choosing transcatheter arterial chemotherapy instead of chemotherapy from oral and intranous injection. The target arteries are arteria mesenterica inferior, right or left arteria iliaca interna and arteria hepatica propria. The chemotherapy drugs are DDP 60 ～ 80 mg, 5～Fu 1000～1500 mg and MMC 8～10mg. There are 18 cases of recur and metastasis of cancer within 5 years, in which 16 cases died of this and 2 cases are still living with cancer. There are not any intestinal necrosis, hemorrage and death because of transcatheter arterial chemotherapy. The living rate in 1,2,3,4,5 years are 94.6%, 85. 7%, 82.1%, 78.6% and 71.4%. The results show that choosing transcathrter arterial chemotherapy can significantly increase the living rate of rectal cancer after radical operation and reduce the rate of recurrence and metastasis of cancer. There is little ADR. We can use choosing transcatheter arterial chemotherapy instead of oral and intranous injection chemotherapy.
出处
《临床消化病杂志》
1998年第3期97-99,共3页
Chinese Journal of Clinical Gastroenterology
关键词
直肠癌
介入导管
靶动脉
生存率
治疗
Rectal cancer Transcatheter Target artery Living rate
